Honkavuori Kirsi S, Shivaprasad H L, Williams Brent L, Quan Phenix Lan, Hornig Mady, Street Craig, Palacios Gustavo, Hutchison Stephen K, Franca Monique, Egholm Michael, Briese Thomas, Lipkin W Ian
Columbia University, New York, NY, USA.
Emerg Infect Dis. 2008 Dec;14(12):1883-6. doi: 10.3201/eid1412.080984.
Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus. Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds.
对患有前胃扩张病(PDD)的鹦鹉大脑中的互补脱氧核糖核酸(cDNA)进行焦磷酸测序,结果显示了两种新型博尔纳病毒毒株。前胃扩张病是一种原因不明的致命性中枢、自主和外周神经系统炎性疾病。实时聚合酶链反应(PCR)证实,3只患有前胃扩张病的鸟类的大脑、前胃和肾上腺中存在该病毒,而4只未受影响的鸟类中则未发现。