Matsuda E, Okabe K, Yagi T, Tao H, Hirazawa K, Murakami T, Sugi K
Department of Chest Surgery, National Hospital Organization Sanyo Hospital, Ube, Japan.
Kyobu Geka. 2008 Nov;61(12):1049-52.
A 53-year-old man admitted to our hospital because of fever and chest abnormal shadow. Chest X-ray and computed tomography (CT) scan revealed large tumor on right upper lobe. Serum interleukin (IL)-6 and granulocyte-colony stimulating factor (G-CSF) were high. Right upper lobectomy and chest wall resection was performed. Histological diagnosis was large cell carcinoma. Immunohistological examination of lung tumor cells showed positive staining for G-CSF in only 1% of them. We diagnosed that tumor was G-CSF producing tumor and we thought that tumor produced IL-6.
一名53岁男性因发热和胸部异常阴影入住我院。胸部X线和计算机断层扫描（CT）显示右上叶有大肿瘤。血清白细胞介素（IL）-6和粒细胞集落刺激因子（G-CSF）升高。行右上叶切除术和胸壁切除术。组织学诊断为大细胞癌。对肺肿瘤细胞进行免疫组织学检查，结果显示仅1%的细胞G-CSF染色呈阳性。我们诊断该肿瘤为产生G-CSF的肿瘤，并认为该肿瘤产生IL-6。
