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婴儿猝死综合征(SIDS)中的重金属、氯化农药和多氯联苯

Heavy metals, chlorinated pesticides and polychlorinated biphenyls in sudden infant death syndrome (SIDS).

作者信息

Kleemann W J, Weller J P, Wolf M, Tröger H D, Blüthgen A, Heeschen W

机构信息

Institut für Rechtsmedizin, Medizinischen Hochschule Hannover, Federal Republic of Germany.

出版信息

Int J Legal Med. 1991 Mar;104(2):71-5. doi: 10.1007/BF01626034.

Abstract

The concentrations of lead in blood and of cadmium and mercury in kidney tissue were determined by atomic absorption spectrometry in cases in SIDS and a control group containing cases of known causes of death. SIDS cases were split into groups from urban and rural areas and areas highly polluted with lead and zinc (sites of lead and zinc works). Neither the concentration of lead in blood (median 26.5 to 50.0 micrograms/l), nor the concentration of cadmium (median 24.0 to 44.0 micrograms/kg ww) or mercury (43.0 to 69.0 micrograms/kg ww) showed significant differences between the groups. In addition the concentrations of persistent chlorohydrocarbons (hexachlorbenzene; alpha, beta and gamma hexachlorcyclohexane; heptachlorepoxide; dieldrine; total DDT; polychlorinated biphenyls) were measured in subcutaneous fatty tissue in SIDS cases from rural and urban areas and in a control group. These substances also showed no significant concentration differences in cases of SIDS.

摘要

采用原子吸收光谱法测定了不明原因婴儿猝死综合征(SIDS)病例以及包含已知死因病例的对照组的血液铅浓度和肾脏组织镉、汞浓度。SIDS病例按城乡地区以及铅锌污染严重地区(铅锌厂所在地)分组。血液铅浓度(中位数为26.5至50.0微克/升)、镉浓度(中位数为24.0至44.0微克/千克湿重)或汞浓度(43.0至69.0微克/千克湿重)在各组之间均未显示出显著差异。此外,还测定了城乡地区SIDS病例及对照组皮下脂肪组织中持久性氯代烃(六氯苯;α、β和γ六氯环己烷;七氯环氧化物;狄氏剂;总滴滴涕;多氯联苯)的浓度。这些物质在SIDS病例中也未显示出显著的浓度差异。

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