Plöckinger B, Dadak C, Meisinger V
2. Univ.-Frauenklinik Wien.
Z Geburtshilfe Perinatol. 1993 Mar-Apr;197(2):104-7.
The objective of the present study was to determine the toxic trace element status of 51 healthy Austrian women and their newborn babies. Lead, mercury and cadmium content of early breast milk, blood and urine were measured post partum by atomic absorption spectrophotometry. None of the toxic trace elements could be found in elevated concentrations; the content of mercury and cadmium in milk was below limits of detection. Mean lead concentration in breast milk was 35.8 (SD:15.0) micrograms/l. Whole blood content of lead was 37.0 (SD:12.7) micrograms/l in mothers and 26.3 (SD:11.6) in newborns. High blood concentrations of mercury were found both in mothers (4.46 micrograms/l, SD:1.95) and in umbilical cord blood (5.58 micrograms/l, SD:2.33). The corresponding values for cadmium were 0.44 (SD:0.4) micrograms/l and 0.08 (SD:0.16) micrograms/l. Urine excretion of the elements assayed was normal. Significant correlations between maternal and neonatal blood toxic mineral levels could be demonstrated in lead (p < 0.001).
本研究的目的是确定51名健康奥地利女性及其新生儿的有毒微量元素状况。产后通过原子吸收分光光度法测量初乳、血液和尿液中的铅、汞和镉含量。未发现任何有毒微量元素浓度升高;牛奶中的汞和镉含量低于检测限。母乳中铅的平均浓度为35.8(标准差:15.0)微克/升。母亲全血铅含量为37.0(标准差:12.7)微克/升,新生儿为26.3(标准差:11.6)微克/升。母亲(4.46微克/升,标准差:1.95)和脐带血(5.58微克/升,标准差:2.33)中均发现高汞血浓度。镉的相应值分别为0.44(标准差:0.4)微克/升和0.08(标准差:0.16)微克/升。所检测元素的尿液排泄正常。在铅方面,可证明母体和新生儿血液有毒矿物质水平之间存在显著相关性(p < 0.001)。