Keyyu J D, Kyvsgaard N C, Monrad J, Kassuku A A
Department of Veterinary Microbiology and Parasitology, Sokoine University of Agriculture, P.O. Box 3019, Morogoro, Tanzania.
Trop Anim Health Prod. 2009 Jan;41(1):25-33. doi: 10.1007/s11250-008-9150-5. Epub 2008 Mar 19.
A longitudinal field trial was conducted to determine the effectiveness of strategic anthelmintic treatments in the control of gastrointestinal (GI) nematodes and Fasciola gigantica in cattle. A total of 167 cattle (6-18 months) from three large-scale dairy farms, four traditional farms and nine small-scale dairy farms were randomly selected. The selected animals on each farm were ear tagged and allocated into three groups based on live weight and treated as follows: Group T4 was treated with albendazole 10% drench at 10 mg/kg four times a year (mid rainy, end of the rain, mid dry and late dry/early rainy season). Group T2 was treated with albendazole 10% drench at 10 mg/kg two times a year (mid rainy and late dry/early rainy season). Group UT remained as untreated control. Faecal, blood and pasture samples were taken every month for 13 months. In addition, individual body weight (BWT) was measured on every sampling date. Results showed that two and four strategic treatments significantly reduced faecal egg counts (FEC) by 49.5% and 62.3% respectively compared to untreated control animals (P < 0.001). Two and four strategic treatments per year significantly reduced the proportion of animals passing Fasciola eggs in faeces by 30.6% and 51.7% (P < 0.001), respectively. Animals treated two and four times a year significantly outgained untreated animals by 14.8 kg and 17.7 kg respectively at the end of the trial (P < 0.05). The management system had a significant effect on packed cell volume and the proportion of animals passing Fasciola eggs in faeces (P < 0.05). The programme of two strategic treatments per year was only effective in controlling GI nematodes. It is concluded that a programme of four strategic treatments per year was effective in controlling GI nematodes and F. gigantica and improved weight gain.
开展了一项纵向田间试验，以确定战略性驱虫治疗对控制牛胃肠道线虫和巨片形吸虫的效果。从三个大型奶牛场、四个传统农场和九个小型奶牛场随机选取了总共167头6至18月龄的牛。每个农场选定的动物都进行了耳标标记，并根据体重分为三组，治疗方式如下：T4组每年用10%的阿苯达唑溶液按10毫克/千克的剂量灌服四次（雨季中期、雨季结束时、旱季中期和旱季后期/雨季初期）。T2组每年用10%的阿苯达唑溶液按10毫克/千克的剂量灌服两次（雨季中期和旱季后期/雨季初期）。UT组作为未治疗的对照组。在13个月的时间里，每月采集粪便、血液和牧场样本。此外，在每个采样日期测量个体体重（BWT）。结果显示，与未治疗的对照动物相比，两次和四次战略性治疗分别使粪便虫卵计数（FEC）显著降低了49.5%和62.3%（P<0.001）。每年两次和四次战略性治疗分别使粪便中排出片形吸虫卵的动物比例显著降低了30.6%和51.7%（P<0.001）。在试验结束时，每年接受两次和四次治疗的动物体重分别比未治疗的动物显著增加了14.8千克和17.7千克（P<0.05）。管理系统对红细胞压积以及粪便中排出片形吸虫卵的动物比例有显著影响（P<0.05）。每年进行两次战略性治疗的方案仅对控制胃肠道线虫有效。得出的结论是，每年进行四次战略性治疗的方案对控制胃肠道线虫和巨片形吸虫有效，并能提高体重增加量。
