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老年人的慢性疼痛与肥胖:爱因斯坦衰老研究的结果

Chronic pain and obesity in elderly people: results from the Einstein aging study.

作者信息

McCarthy Lucas H, Bigal Marcelo E, Katz Mindy, Derby Carol, Lipton Richard B

机构信息

Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.

出版信息

J Am Geriatr Soc. 2009 Jan;57(1):115-9. doi: 10.1111/j.1532-5415.2008.02089.x. Epub 2008 Nov 19.

Abstract

OBJECTIVES

To determine the prevalence of chronic pain in elderly people and its relationship with obesity and associated comorbidities and risk factors.

DESIGN

Cross-sectional.

SETTING

Community.

PARTICIPANTS

A representative community sample of 840 subjects aged 70 and older.

MEASUREMENTS

The prevalence of chronic pain and its relationship with obesity (categories defined according to body mass index (BMI)), other medical risk factors, and psychiatric comorbidities were examined. Chronic pain was defined as pain of at least moderate severity (> or =4 on a 10-point scale) some, most, or all of the time for the previous 3 months.

RESULTS

The sample was mostly female (62.8%), and the average age was 80 (range 70-101). The prevalence of chronic pain was 52% (39.7% in men; 58.9% in women). Subjects with chronic pain were more likely to report a diagnosis of depression (odds ratio (OR)=2.5, 95% confidence interval (CI)=1.40-4.55) and anxiety (OR=2.3, 95% CI=1.22-4.64). Obese subjects (BMI 30-34.9) were twice as likely (OR=2.1, 95%CI=1.33-3.28) and severely obese subjects (BMI> or =35) were more than four times as likely (OR=4.5, 95% CI=1.85-12.63) as those of normal weight (BMI 18.5-24.9) to have chronic pain. Obese subjects were significantly more likely to have chronic pain in the head, neck or shoulder, back, legs or feet, and abdomen or pelvis than subjects who were not obese. In multivariate models, obesity (OR=2.0, 95% CI=1.27-3.26) and severe obesity (OR=4.1, 95% CI=1.57-10.82) were associated with chronic pain after adjusting for age, sex, diabetes mellitus, hypertension, depression, anxiety, and education.

CONCLUSION

Chronic pain is common in this elderly population, affects women more than men, and is highly associated with obesity.

摘要

目的

确定老年人慢性疼痛的患病率及其与肥胖、相关合并症和危险因素的关系。

设计

横断面研究。

地点

社区。

参与者

840名70岁及以上的具有代表性的社区样本。

测量

检查慢性疼痛的患病率及其与肥胖(根据体重指数(BMI)定义类别)、其他医学危险因素和精神合并症的关系。慢性疼痛定义为在过去3个月中的某些、大部分或全部时间里至少为中度严重程度(10分制中≥4分)的疼痛。

结果

样本中女性居多(62.8%),平均年龄为80岁(范围70 - 101岁)。慢性疼痛的患病率为52%(男性为39.7%;女性为58.9%)。患有慢性疼痛的受试者更有可能报告患有抑郁症(比值比(OR)=2.5,95%置信区间(CI)=1.40 - 4.55)和焦虑症(OR = 2.3,95% CI = 1.22 - 4.64)。肥胖受试者(BMI 30 - 34.9)患慢性疼痛的可能性是正常体重受试者(BMI 18.5 - 24.9)的两倍(OR = 2.1,95% CI = 1.33 - 3.28),而重度肥胖受试者(BMI≥35)患慢性疼痛的可能性是正常体重受试者的四倍多(OR = 4.5,95% CI = 1.85 - 12.63)。与非肥胖受试者相比,肥胖受试者在头部、颈部或肩部、背部、腿部或脚部以及腹部或骨盆处出现慢性疼痛的可能性显著更高。在多变量模型中,在调整年龄、性别、糖尿病、高血压、抑郁症、焦虑症和教育程度后,肥胖(OR = 2.0,95% CI = 1.27 - 3.26)和重度肥胖(OR = 4.1,95% CI = 1.57 - 10.82)与慢性疼痛相关。

结论

慢性疼痛在该老年人群中很常见,对女性的影响大于男性,并且与肥胖高度相关。

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本文引用的文献

1
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2
Comorbidity of obesity and pain in a general population: results from the Southern Pain Prevalence Study.
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3
Pain in aging community-dwelling adults in the United States: non-Hispanic whites, non-Hispanic blacks, and Hispanics.
J Pain. 2007 Jan;8(1):75-84. doi: 10.1016/j.jpain.2006.06.002. Epub 2006 Sep 1.
4
Leukocytosis in obese individuals: possible link in patients with unexplained persistent neutrophilia.
Eur J Haematol. 2006 Jun;76(6):516-20. doi: 10.1111/j.1600-0609.2006.00658.x.
5
Prevalence, interference, and risk factors for chronic pain among Taiwanese community older people.
Pain Manag Nurs. 2006 Mar;7(1):2-11. doi: 10.1016/j.pmn.2005.12.002.
6
Obesity and migraine: a population study.
Neurology. 2006 Feb 28;66(4):545-50. doi: 10.1212/01.wnl.0000197218.05284.82. Epub 2005 Dec 14.
7
Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment.
Eur J Pain. 2006 May;10(4):287-333. doi: 10.1016/j.ejpain.2005.06.009. Epub 2005 Aug 10.
8
Prevalence of clinical hypertension in patients with chronic pain compared to nonpain general medical patients.
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9
Prevalence and characteristics of chronic pain in the general Norwegian population.
Eur J Pain. 2004 Dec;8(6):555-65. doi: 10.1016/j.ejpain.2004.02.002.
10
Obesity and the impact of chronic pain.
Clin J Pain. 2004 May-Jun;20(3):186-91. doi: 10.1097/00002508-200405000-00009.

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