Ogden A R, Pinhasi R, White W J
Biological Anthropology Research Centre, Archaeological Sciences, University of Bradford, Bradford; West Yorkshire, BD7 1DP, England.
Eur Arch Paediatr Dent. 2008 Dec;9(4):166-71. doi: 10.1007/BF03262632.
This was to study an archaeological population of subadult teeth in 17th and 18th century skeletal material from a London (England) cemetery for enamel defects including molar-incisor-hypomineralisation (MIH).
Dentitions of 45 sub-adults were examined using standard macroscopic methods and systematically recorded. A total of 557 teeth were examined with a *5 lens and photographed. Ages of the individuals were estimated from their dental crown and root development stages and not from charts that combine tooth eruption with development stages. The dental age of the individual and the approximate age of onset of enamel defects was then calculated on the basis of the chronological sequence of incremental deposition and calcification of the enamel matrix. Affected enamel was graded macroscopically as: - Mild: <30% of the tooth's enamel surface area visibly disrupted (this encompasses the entire range reported in most other studies), Moderate: 31-49% of the tooth's enamel surface area visibly disrupted and Severe: >50% of the tooth's enamel surface area visibly disrupted.
Of the total number of individuals 41 (93.2%) showed signs of enamel developmental dysplasia or MIH, 28 of them showing moderate or severe lesions of molars, primary or permanent (63.6% of the sample). Incisors and canines, though surviving much less often, showed episodes of linear hypoplasia.
The extensive lesions seen on many of the molars displayed cuspal enamel hypoplasia (CEH). Many of these teeth also exhibited Molar Incisal Hypomineralisation (MIH).
本研究旨在对来自伦敦（英国）一座公墓的17和18世纪骨骼材料中的亚成体牙齿考古样本进行研究，以了解包括磨牙-切牙矿化不全（MIH）在内的牙釉质缺陷情况。
采用标准宏观方法对45名亚成体的牙列进行检查并系统记录。使用5倍放大镜对总共557颗牙齿进行检查并拍照。根据个体的牙冠和牙根发育阶段而非结合牙齿萌出与发育阶段的图表来估计个体年龄。然后根据牙釉质基质增量沉积和钙化的时间顺序计算个体的牙龄以及牙釉质缺陷的大致发病年龄。对受影响的牙釉质进行宏观分级为：轻度：牙齿牙釉质表面积可见破坏小于30%（这涵盖了大多数其他研究报告的整个范围），中度：牙齿牙釉质表面积可见破坏31%-49%，重度：牙齿牙釉质表面积可见破坏大于50%。
在所有个体中，41名（93.2%）显示出牙釉质发育异常或MIH的迹象，其中28名显示出磨牙（乳牙或恒牙）的中度或重度病变（占样本的63.6%）。切牙和尖牙虽然留存较少，但也出现了线性发育不全的情况。
许多磨牙上出现的广泛病变表现为牙尖釉质发育不全（CEH）。这些牙齿中的许多还表现出磨牙-切牙矿化不全（MIH）。
