Chawla N, Messer L B, Silva M
Dept. Paediatric Dentistry, Melbourne Dental School, The University of Melbourne, 720 Swanston Street, Victoria 3010, Australia.
Eur Arch Paediatr Dent. 2008 Dec;9(4):180-90. doi: 10.1007/BF03262634.
This was to describe the distributions of affected first permanent molars (FPMs) in a sample of children with molarincisor- hypomineralisation (MIH) and molar hypomineralisation (MH), and to examine their perinatal and medical histories for putative associations with molar hypomineralisation.
A sample of 416 children aged 6-14 years with MIH or MH was identified from a specialist paediatric dental practice in Melbourne, Australia.
A questionnaire regarding perinatal and medical histories was sent to their parents/guardians; 182 (44%) useable questionnaires were returned and the dental records of these children were reviewed.
The 182 dentitions were distributed as: MIH: 104; MH: 65; MIH* (permanent incisors unerupted): 13. These dentitions contained 720 FPMs; 429 FPMs were hypomineralised, distributed as: MIH: 282 FPMs; MH: 124 FPMs; MIH*: 23 FPMs. The 282 affected FPMs occurred in dentitions with MIH as: 1 FPM: 27%; 2 FPMs: 15%; 3 FPMs: 17%; 4 FPMs: 40% (mean 2.7 +/- 1.3 FPMs/dentition). The 124 affected FPMs occurred in dentitions with MH as: 1 FPM: 49%; 2 FPMs: 28%; 3 FPMs: 6%; 4 FPMs: 17% (mean 1.9 +/- 1.1 FPMs/dentition). The distribution of moderate to severe hypomineralisation in FPMs was: MIH: 89%; MH: 73%. Affected FPMs were similarly distributed between gender, quadrants and arches. At least one condition putatively associated with MIH/MH was seen in histories of 166 children (91%); ear infections, fevers, and perinatal conditions occurred in 53-66% of children. Frequent condition combinations were: ear infections + fevers (40% of children); antibiotics + ear infections (54%); antibiotics + other illnesses (56%).
All four FPMs in a given dentition were more likely to be affected and to differing extents in MIH than in MH. Putative associations appear to exist between MIH/MH and combinations of antibiotic use, ear infections, fevers, perinatal conditions, and other illnesses in the child's first 3 years. It is proposed that MIH is a more severe form of the hypomineralisation condition than MH, forming an MIH spectrum.
描述患有磨牙-切牙矿化不全（MIH）和磨牙矿化不全（MH）的儿童样本中受影响的第一恒磨牙（FPM）的分布情况，并检查其围产期和病史，以寻找与磨牙矿化不全的可能关联。
从澳大利亚墨尔本的一家专科儿童牙科诊所中确定了416名6至14岁患有MIH或MH的儿童样本。
向他们的父母/监护人发送了一份关于围产期和病史的问卷；共返回182份（44%）可用问卷，并对这些儿童的牙科记录进行了审查。
182副牙列分布如下：MIH：104例；MH：65例；MIH*（恒牙切牙未萌出）：13例。这些牙列包含720颗FPM；429颗FPM矿化不全，分布如下：MIH：282颗FPM；MH：124颗FPM；MIH*：23颗FPM。282颗受影响的FPM出现在患有MIH的牙列中的情况为：1颗FPM：27%；2颗FPM：15%；3颗FPM：17%；4颗FPM：40%（平均每副牙列2.7±1.3颗FPM）。124颗受影响的FPM出现在患有MH的牙列中的情况为：1颗FPM：49%；2颗FPM：28%；3颗FPM：6%；4颗FPM：17%（平均每副牙列1.9±1.1颗FPM）。FPM中中度至重度矿化不全的分布为：MIH：89%；MH：73%。受影响的FPM在性别、象限和牙弓之间的分布相似。166名儿童（91%）的病史中至少有一种可能与MIH/MH相关的情况；53 - 66%的儿童有耳部感染、发热和围产期疾病。常见的情况组合为：耳部感染 + 发热（40%的儿童）；抗生素 + 耳部感染（54%）；抗生素 + 其他疾病（56%）。
在给定的牙列中，所有四颗FPM在MIH中比在MH中更有可能受到影响且程度不同。MIH/MH与儿童出生后头3年中抗生素使用、耳部感染、发热、围产期疾病和其他疾病的组合之间似乎存在可能的关联。有人提出，MIH是矿化不全状况比MH更严重的一种形式，形成了一个MIH谱。
