Hosoido Taisei, Motoyama Sachiko, Goto Megumi, Mori Futoshi, Tajima Takamitsu, Hirata Hajime, Wada Naomi
Osaka Veterinary Referral Center, Osaka City 537-0025, Japan.
Neurosci Lett. 2009 Feb 6;450(3):239-41. doi: 10.1016/j.neulet.2008.11.045. Epub 2008 Nov 25.
The Hoffman reflex (H-reflex) is a useful tool for studying the functional aspects of the spinal cord without anesthesia and/or damage to the body. H-reflex studies are performed mainly in the hindlimbs. The purpose of the present study was to evaluate the characteristics of the H-reflex in the forelimbs and hindlimbs in rats anesthetized with ketamine-HCl. H- and M-waves were recorded from the interosseous muscles after electrical stimulation of the n. lateral plantar of the hindlimb and n. medialis of the forelimb. Hmax/Mmax values were significantly smaller in the forelimbs than in the hindlimbs. Furthermore, paired-pulse attenuation tended to be stronger in the forelimbs than in the hindlimbs. These findings suggest that control by descending and/or propriospinal pathways is stronger in the forelimbs than in the hindlimbs in rats.
霍夫曼反射（H反射）是一种在不进行麻醉和/或不损伤身体的情况下研究脊髓功能方面的有用工具。H反射研究主要在大鼠后肢进行。本研究的目的是评估用氯胺酮-盐酸麻醉的大鼠前肢和后肢H反射的特征。在电刺激后肢足底外侧神经和前肢内侧神经后，从骨间肌记录H波和M波。前肢的Hmax/Mmax值显著小于后肢。此外，前肢的双脉冲衰减往往比后肢更强。这些发现表明，在大鼠中，前肢下行和/或脊髓 propriospinal 通路的控制比后肢更强。
