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腰椎管狭窄症非手术治疗的临床结局及与预后相关的预测因素:至少5年的随访研究

Clinical outcome of nonoperative treatment for lumbar spinal stenosis, and predictive factors relating to prognosis, in a 5-year minimum follow-up.

作者信息

Miyamoto Hiroshi, Sumi Masatoshi, Uno Koki, Tadokoro Kou, Mizuno Kiyonori

机构信息

Department of Orthopaedic Surgery, National Hospital Organization Kobe Medical Center, Kobe, Japan.

出版信息

J Spinal Disord Tech. 2008 Dec;21(8):563-8. doi: 10.1097/BSD.0b013e31815d896c.

Abstract

STUDY DESIGN

A prospective long-term follow-up study of nonoperative treatment for lumbar spinal stenosis (LSS) and multivariable analysis of the prognosis.

OBJECTIVES

To clarify the outcomes of nonoperative treatment for LSS over a long-term follow-up, and to extrapolate factors relating to the prognosis of treatment.

SUMMARY OF BACKGROUND DATA

The indicators of treatment for LSS remain controversial, and few reports have evaluated the prognosis of its nonoperative treatment, or extrapolated the factors that aid prognosis.

METHODS

One hundred twenty patients who received inpatient nonoperative treatment were followed up for 5 years or longer. Patients' nerve involvement and myelographic findings were classified, and the disturbance level of activities of daily living (ADL) at final follow-up was graded. The association between patients' age and sex, classification of nerve involvement and myelographic findings, recovery rate by initial nonoperative treatment, presence or absence of degenerative spondylolisthesis/scoliosis, and disturbance level of ADL were evaluated statistically to extrapolate prognostic factors.

RESULTS

In all, 52.5% of patients showed no hindrance to ADL at follow-up. Patients who were classified as radicular type, or responded well to initial nonoperative treatment, exhibited statistically better results than did other patients. In contrast, accompanying degenerative scoliosis tended to be related to a poorer prognosis.

CONCLUSION

The current study demonstrated the long-term follow-up outcome of nonoperative treatment for LSS. Important factors relating to the prognosis were demonstrated. These factors could aid the decision-making process for treatment of LSS patients.

摘要

研究设计

腰椎管狭窄症(LSS)非手术治疗的前瞻性长期随访研究及预后的多变量分析。

目的

明确LSS非手术治疗的长期随访结果,并推断与治疗预后相关的因素。

背景资料总结

LSS的治疗指标仍存在争议,很少有报告评估其非手术治疗的预后,或推断有助于预后的因素。

方法

对120例接受住院非手术治疗的患者进行了5年或更长时间的随访。对患者的神经受累情况和脊髓造影结果进行分类,并对末次随访时的日常生活活动(ADL)障碍程度进行分级。对患者的年龄和性别、神经受累和脊髓造影结果的分类、初始非手术治疗的恢复率、是否存在退行性椎体滑脱/脊柱侧凸以及ADL障碍程度之间的关联进行统计学评估,以推断预后因素。

结果

总体而言,52.5%的患者在随访时ADL无障碍。分类为神经根型或对初始非手术治疗反应良好的患者,其结果在统计学上优于其他患者。相比之下,伴有退行性脊柱侧凸往往与较差的预后相关。

结论

本研究展示了LSS非手术治疗的长期随访结果。证明了与预后相关的重要因素。这些因素有助于LSS患者治疗的决策过程。

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