Bellizzi Keith M, Mustian Karen M, Palesh Oxana G, Diefenbach Michael
Human Development and Family Studies, University of Connecticut, Storrs, Connecticut 06269-2058, USA.
Cancer. 2008 Dec 15;113(12 Suppl):3530-9. doi: 10.1002/cncr.23942.
Given the high incidence and prevalence of cancer in older adults and the anticipated growth of this population over the next few decades, oncologists, geriatricians, and primary care providers will be challenged to provide timely and appropriate post-treatment care to a diverse population of older cancer survivors. To the authors' knowledge to date, few post-treatment epidemiologic or clinical trial studies have investigated the mental, social, and physical health issues among older cancer survivors. For this article, the authors reviewed the behavioral oncology, gerontology, geriatric, and psychology literature on cancer survivorship and aging. This report highlights several methodologic challenges that investigators face when conducting epidemiologic and cancer clinical trial research with older cancer survivors after treatment. These challenges must be considered and overcome to develop an informative body of scientific knowledge to address the post-treatment healthcare needs of this growing population. Future research directions, new models of care, and the need for transdisciplinary approaches are discussed.
鉴于癌症在老年人中的高发病率和患病率，以及预计在未来几十年中该人群的增长，肿瘤学家、老年病学家和初级保健提供者将面临挑战，即要为不同的老年癌症幸存者群体提供及时且适当的治疗后护理。据作者所知，迄今为止，很少有治疗后流行病学或临床试验研究调查老年癌症幸存者的心理、社会和身体健康问题。在撰写本文时，作者回顾了关于癌症幸存者和衰老的行为肿瘤学、老年医学、老年病学及心理学文献。本报告强调了研究人员在对接受治疗后的老年癌症幸存者进行流行病学和癌症临床试验研究时所面临的几个方法学挑战。为了形成有助于满足这一不断增长人群治疗后医疗保健需求的科学知识体系，必须考虑并克服这些挑战。文中还讨论了未来的研究方向、新的护理模式以及跨学科方法的必要性。
