Goldring Steven R
The Hospital for Special Surgery, Weill College of Medicine of Cornell University, 535 East 70th Street, New York, NY 10021, USA.
Med Clin North Am. 2009 Jan;93(1):25-35, xv. doi: 10.1016/j.mcna.2008.09.006.
Much of the attention in developing diagnostic tools and therapeutic interventions for the management of osteoarthritis (OA) has focused on the preservation or repair of articular cartilage. It is clear that all of the joint components, including the ligaments, tendons, capsule, synovial lining, and periarticular bone, undergo structural and functional alterations during the course of OA progression. This article focuses on the specific skeletal features of OA and the putative mechanisms involved in their pathogenesis.
在开发用于骨关节炎（OA）管理的诊断工具和治疗干预措施方面，大部分注意力都集中在关节软骨的保存或修复上。很明显，在OA进展过程中，所有关节组件，包括韧带、肌腱、关节囊、滑膜衬里和关节周围骨骼，都会发生结构和功能改变。本文重点关注OA的特定骨骼特征及其发病机制中涉及的假定机制。
