Manicourt D H, Devogelaer J P, Azria M, Silverman S
Department of Rheumatology, University Hospital St Luc, Universite Catholique de Louvain, Brussels, Belgium.
J Musculoskelet Neuronal Interact. 2005 Jul-Sep;5(3):285-93.
This review provides evidence that osteoarthritis (OA) or a major subset of OA is not only a disease of cartilage but also a disorder of subchondral bone. This review also discusses the potential efficacy of a bone and cartilage active agent, calcitonin, and discusses how calcitonin might be useful in the pharmaceutical treatment of OA.
本综述提供的证据表明,骨关节炎(OA)或OA的一个主要亚类不仅是软骨疾病,也是软骨下骨疾病。本综述还讨论了一种骨与软骨活性剂——降钙素的潜在疗效,并探讨了降钙素在OA药物治疗中可能如何发挥作用。