Fan Song-Qing, Liang Qing-Chun, Jiang Yi
Department of Pathology, Second Xiang Ya Hospital of Central South University, 156 Ren-Min Road, Changsha, Hunan 410011, China.
Int J Surg. 2008 Dec;6(6):462-4. doi: 10.1016/j.ijsu.2006.05.011. Epub 2006 Jun 19.
We report a case of congenital benign thyroid teratoma in an 11-month-old male infant who was found to have right thyroid gland mass since birth. The tumor was 25 x 20 x 15 mm with whole thin capsule and could be easily dissected from the surrounding normal thyroid tissue at surgery. Histologically, tumor had mature derivatives of the three primordial germ layers with a variety of benign and well-differentiated elements. It was the most conspicuous feature that the tumor was composed mainly of the neurological tissue resembling brain tissue with glial cells and ependymal epithelium components. There were a few anastomosing variably sized tubules and cysts lined by ependymal epithelial cells with papillary feature and retinal pigment epithelial cells. In summary, benign teratoma of thyroid gland in an 11-month-old infant was morphologically and immunophenotypically identified.
我们报告一例11个月大男婴的先天性良性甲状腺畸胎瘤，该男婴自出生以来就被发现右甲状腺有肿块。肿瘤大小为25×20×15毫米，有完整的薄包膜，手术时可轻松从周围正常甲状腺组织中分离出来。组织学上，肿瘤具有三个原始胚层的成熟衍生物，包含多种良性且分化良好的成分。最显著的特征是肿瘤主要由类似脑组织的神经组织组成，含有神经胶质细胞和室管膜上皮成分。还有一些相互吻合、大小不一的小管和囊肿，内衬具有乳头特征的室管膜上皮细胞和视网膜色素上皮细胞。总之，对一名11个月大婴儿的甲状腺良性畸胎瘤进行了形态学和免疫表型鉴定。
