Mochizuki Y, Noguchi S, Yokoyama S, Murakami N, Moriuchi A, Aisaka K, Yamashita H, Nakayama I
Acta Pathol Jpn. 1986 Jun;36(6):935-43. doi: 10.1111/j.1440-1827.1986.tb03127.x.
Two cases of cervical teratoma in a 30-weeks fetus and a 26-year-old female have been presented. In the former case a large mass entirely occupied the anterior neck but showed no invasive or metastatic lesions, and in the other case a mass containing multiple cysts was situated in the right lower pole of the thyroid gland. Histologically, both tumors were composed of the elements derived from three germ layers including various epithelial components, cartilage, muscle, and adipose tissue. In addition to these predominantly mature elements, there were some elements showing primitive immature structure in the former case. Positive immunohistochemical staining for thyroglobulin displayed only in the former case and was observed in the compressed thyroid follicles located in the fibrous capsule and several small foci of primitive glandular structure which was an element of the tumor.
本文报告了两例畸胎瘤病例，一例发生于一名30周大的胎儿，另一例发生于一名26岁女性。前一例中，一个巨大肿块完全占据了前颈部，但未显示侵袭性或转移性病变；另一例中，一个含有多个囊肿的肿块位于甲状腺右下极。组织学上，这两个肿瘤均由来自三个胚层的成分组成，包括各种上皮成分、软骨、肌肉和脂肪组织。除了这些主要为成熟的成分外，前一例中还有一些显示原始未成熟结构的成分。甲状腺球蛋白免疫组化染色仅在前一例中呈阳性，在位于纤维包膜内的受压甲状腺滤泡以及肿瘤成分之一的几个原始腺结构小灶中观察到。
