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恒牙先天缺失:一项关于美国黑人和白人的流行病学研究。

Hypodontia: an epidemiologic study of American black and white people.

作者信息

Harris Edward F, Clark Larkin L

机构信息

Department of Orthodontics, College of Dentistry, University of Tennessee, Memphis, TN 38163, USA.

出版信息

Am J Orthod Dentofacial Orthop. 2008 Dec;134(6):761-7. doi: 10.1016/j.ajodo.2006.12.019.

DOI:10.1016/j.ajodo.2006.12.019
PMID:19061802
Abstract

INTRODUCTION

There are numerous epidemiologic studies of hypodontia, but most focus on white populations that, because of small teeth and slow development, might not represent the status of other peoples. The purpose of this study was to contrast the distributions of hypodontia in an adolescent sample of American blacks (n=600) with a comparable sample of whites (n=1100).

METHODS

Panoramic radiographs of 1700 unrelated adolescents between 12 and 18 years were scrutinized for hypodontia. Those with syndromes and major genes contributing to congenital absence were omitted.

RESULTS

The prevalence of people with missing teeth is significantly lower in blacks (11%) than in whites (27%), as is the number of missing teeth per person. When all tooth types were combined for a summary value, the frequency of missing teeth in whites (1.5% of the expected 32 teeth per person) was significantly higher than in blacks (0.6%), with an odds ratio of 2.52 (95% confidence limits [CL]: 2.07, 3.08). Differences between black and white people are disproportionately large where hypodontia is most common, notably in 2 tooth types: (1) the difference is statistically significant for third molars, with the odds ratio 3.18 higher in whites (CL: 2.43, 4.17) for all quadrants combined, and (2) for second premolars (combining all quadrants), whites are 1.75 times more likely to exhibit congenital absence (CL: 1.06, 2.90). In contrast, significant sex differences were found only for the third molars (absence more common in females), and the sex differences were greater in whites than in blacks.

CONCLUSIONS

Extrapolations from the literature, based largely of studies of white subjects, do not readily apply to American blacks or, potentially, to other racial groups.

摘要

引言

关于缺牙症已有大量流行病学研究,但大多数研究聚焦于白人群体,而由于白种人的牙齿较小且发育缓慢,可能无法代表其他人群的状况。本研究的目的是对比美国黑人青少年样本(n = 600)和与之匹配的白人样本(n = 1100)中缺牙症的分布情况。

方法

对1700名年龄在12至18岁的非亲属青少年的全景X线片进行缺牙症检查。排除患有综合征以及由主要基因导致先天性缺牙的个体。

结果

黑人中牙齿缺失者的患病率(11%)显著低于白人(27%),每人缺失牙齿的数量也是如此。当将所有牙型合并以得出一个汇总值时,白人中缺失牙齿的频率(每人预期32颗牙中的1.5%)显著高于黑人(0.6%),优势比为2.52(95%置信区间[CL]:2.07,3.08)。在缺牙症最常见的两种牙型中,黑人和白人之间的差异尤为显著:(1)对于第三磨牙,差异具有统计学意义,所有象限合并计算时,白人的优势比高3.18(CL:2.43,4.17);(2)对于第二前磨牙(所有象限合并),白人出现先天性缺失的可能性是黑人的1.75倍(CL:1.06,2.90)。相比之下,仅在第三磨牙上发现了显著的性别差异(女性缺失更为常见),且白人中的性别差异大于黑人。

结论

基于对白种人的研究得出的文献推断,并不容易适用于美国黑人,甚至可能不适用于其他种族群体。

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