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结膜缝线拆除对小梁切除术结果的影响。

Influence of conjunctival suture removal on the outcome of trabeculectomy.

作者信息

Klink Thomas, Rauch Nicola, Klink Janine, Grehn Franz

机构信息

University Eye Hospital, Wurzburg, Germany.

出版信息

Ophthalmologica. 2009;223(2):116-23. doi: 10.1159/000181150. Epub 2008 Dec 10.

Abstract

BACKGROUND

To evaluate the influence of early conjunctival suture removal following trabeculectomy on postoperative outcome.

METHODS

In a prospective randomized clinical trial 73 eyes of 69 consecutive patients eligible for primary trabeculectomy were included in the study. Eyes were randomly assigned to a control or intervention group. Trabeculectomy was performed with a fornix-based conjunctival flap and a conjunctival running mattress-suture. In the intervention group, the conjunctival suture was removed 4 weeks postoperatively, in the control group the suture remained in place. Both groups were followed for up to 12 months and best corrected visual acuity (BCVA), refraction, corneal topography, intraocular pressure (IOP), anterior segment and fundus were assessed preoperatively and within a week, 1, 3, 6 and 12 months after surgery. Statistical analysis was performed using SPSS for Windows (t test for independent samples).

RESULTS

Trabeculectomy induced similar astigmatism in both groups. Compared to the control group, suture removal seemed to improve BCVA at 6 and 12 months. This was associated with a significantly lower IOP at 6 and 12 months and a significantly higher complete success rate at 12 months (94 vs. 65%, p < 0.001). Astigmatism was not significantly altered by suture removal.

CONCLUSION

Conjunctival suture material appears to hamper trabeculectomy success and postoperative visual acuity. This is independent of postoperative astigmatism. Early removal of conjunctival sutures is advisable.

摘要

背景

评估小梁切除术后早期拆除结膜缝线对术后结果的影响。

方法

在一项前瞻性随机临床试验中,纳入了69例符合原发性小梁切除术条件的连续患者的73只眼。将眼随机分为对照组或干预组。采用以穹窿为基底的结膜瓣和结膜连续褥式缝线进行小梁切除术。在干预组中,术后4周拆除结膜缝线,对照组缝线保留原位。两组均随访12个月,术前及术后1周、1、3、6和12个月评估最佳矫正视力(BCVA)、屈光、角膜地形图、眼压(IOP)、眼前段和眼底。使用SPSS for Windows进行统计分析(独立样本t检验)。

结果

小梁切除术在两组中引起相似的散光。与对照组相比,拆除缝线似乎在6个月和12个月时改善了BCVA。这与6个月和12个月时显著较低的眼压以及12个月时显著较高的完全成功率相关(94%对65%,p<0.001)。拆除缝线未显著改变散光。

结论

结膜缝线材料似乎会妨碍小梁切除术的成功和术后视力。这与术后散光无关。建议早期拆除结膜缝线。

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