Kim Chan Gyoo, Choi Il Ju, Lee Jong Yeul, Cho Soo-Jeong, Lee Jun Ho, Ryu Keun Won, Park Sook Ryun, Bae Jae-Moon, Kim Young-Woo
Research Institute and Hospital, National Cancer Center, Goyang, Korea.
Surg Endosc. 2009 Aug;23(8):1775-80. doi: 10.1007/s00464-008-0224-2. Epub 2008 Dec 6.
Benign strictures at esophagojejunostomy sites may develop after total gastrectomy, and through-the-scope balloon dilation (TTS-BD) can relieve them. The aim of this study was to evaluate effective and safe balloon diameter for benign stricture after total gastrectomy.
From June 2001 to December 2006, 930 gastric cancer patients underwent total gastrectomy with Roux-en-Y esophagojejunostomy in a cancer center hospital. We performed TTS-BD when benign strictures developed. Initial success rate, complication rate, and restenosis rate were evaluated. We classified the patients into three groups according to final dilation diameter and number of sessions.
A total of 58 patients (6.2%) developed a benign stricture at the esophagojejunostomy site. We classified them into three groups based on the final luminal diameter of the balloon used and the number of sessions, as follows: group A (n = 20), 13.5-15 mm in one or two sessions; group B (n = 13), 16.5-20 mm in one session; group C (n = 25), 16.5-20 mm in two sessions. The initial success rates were 100% for groups A and B and 96% for group C. A perforation occurred in one patient (7.7%) in group B. Restenosis occurred in two patients (10%) in group A, one patient (7.7%) in group B, and in no patients in group C (p = 0.29). Restenosis was resolved by one or two further TTS-BDs.
TTS-BD to 15 mm was a safe and effective treatment for benign esophagojejunostomy strictures following total gastrectomy. Restenosis was not common and could be resolved by one or two further TTS-BD sessions.
全胃切除术后可能会在食管空肠吻合口处出现良性狭窄,经内镜球囊扩张术(TTS-BD)可缓解此类狭窄。本研究旨在评估全胃切除术后良性狭窄的有效且安全的球囊直径。
2001年6月至2006年12月,930例胃癌患者在某癌症中心医院接受了全胃切除及Roux-en-Y食管空肠吻合术。当出现良性狭窄时,我们进行了经内镜球囊扩张术。评估初始成功率、并发症发生率和再狭窄率。我们根据最终扩张直径和扩张次数将患者分为三组。
共有58例患者(6.2%)在食管空肠吻合口处出现良性狭窄。我们根据所用球囊的最终腔径和扩张次数将他们分为三组,如下:A组(n = 20),在一或两次扩张中直径为13.5 - 15毫米;B组(n = 13),在一次扩张中直径为16.5 - 20毫米;C组(n = 25),在两次扩张中直径为16.5 - 20毫米。A组和B组的初始成功率为100%,C组为96%。B组有1例患者(7.7%)发生穿孔。A组有2例患者(10%)发生再狭窄,B组有1例患者(7.7%)发生再狭窄,C组无患者发生再狭窄(p = 0.29)。通过一或两次进一步的经内镜球囊扩张术可解决再狭窄问题。
对于全胃切除术后食管空肠吻合口良性狭窄,扩张至15毫米的经内镜球囊扩张术是一种安全有效的治疗方法。再狭窄并不常见,通过一或两次进一步的经内镜球囊扩张术即可解决。