单核细胞增生李斯特菌的模式菌株：持续存在困难的一个来源。
The type strain(s) of Listeria monocytogenes: a source of continuing difficulties.
作者信息
Kathariou S, Pine L
机构信息
Division of Bacterial Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
出版信息
Int J Syst Bacteriol. 1991 Apr;41(2):328-30. doi: 10.1099/00207713-41-2-328.
The type strain of Listeria monocytogenes differs from wild-type L. monocytogenes strains in more characteristics than just the previously reported deficiency in hemolytic activity and virulence in the murine infection model. The type strain from the American Type Culture Collection (strain ATCC 15313) produces lecithinase, is hemolytic on rabbit (but not sheep) blood agar, lacks motility, and shows limited cytopathogenic effects on Caco-2 monolayers, whereas the type strain from the Special Listeria Culture Collection (strain SLCC 53) is unable to produce lecithinase, is nonhemolytic on rabbit or sheep blood agar, is motile, and shows no cytopathogenic effects on Caco-2 monolayers.
产单核细胞李斯特菌的模式菌株与野生型产单核细胞李斯特菌菌株在更多特征上存在差异，而不仅仅是先前报道的在溶血活性和小鼠感染模型中的毒力缺陷。美国典型培养物保藏中心的模式菌株（菌株ATCC 15313）可产生卵磷脂酶，在兔血琼脂上溶血（但不在绵羊血琼脂上溶血），无运动性，并且对Caco-2单层细胞显示出有限的细胞致病作用，而特殊李斯特菌培养物保藏中心的模式菌株（菌株SLCC 53）不能产生卵磷脂酶，在兔或绵羊血琼脂上不溶血，有运动性，并且对Caco-2单层细胞无细胞致病作用。
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