rbcR [rcbR的校正]是一种编码转录调节因子LysR家族成员的基因，位于光合细菌嗜硫小红卵菌中1,5-二磷酸核酮糖羧化酶/加氧酶基因表达集的上游。
rbcR [correction of rcbR], a gene coding for a member of the LysR family of transcriptional regulators, is located upstream of the expressed set of ribulose 1,5-bisphosphate carboxylase/oxygenase genes in the photosynthetic bacterium Chromatium vinosum.
作者信息
Viale A M, Kobayashi H, Akazawa T, Henikoff S
机构信息
Departamento de Microbiologia, Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional de Rosario, Argentina.
出版信息
J Bacteriol. 1991 Aug;173(16):5224-9. doi: 10.1128/jb.173.16.5224-5229.1991.
Abstract
An open reading frame, rbcR, was identified 226 bp upstream of rbcAB, i.e., the ribulose 1,5-bisphosphate carboxylase genes expressed in the phototrophic purple bacterium Chromatium vinosum. Several features reveal that rbcR encodes a member of the LysR family of transcriptional regulators, in which an anomalous content of lysine and arginine residues (Lys/Arg anomaly) was found. The expression of rbcR in Escherichia coli as a protein fused to the N-terminal region of beta-galactosidase led to reduced expression of rbcAB. Thus, rbcR is likely to encode a trans-acting transcriptional regulator of rbcAB expression in C. vinosum.
摘要
在光合紫色细菌嗜硫小红卵菌（Chromatium vinosum）中表达的1,5-二磷酸核酮糖羧化酶基因rbcAB上游226 bp处鉴定出一个开放阅读框rbcR。若干特征表明rbcR编码转录调节因子LysR家族的一个成员，其中发现赖氨酸和精氨酸残基含量异常（赖氨酸/精氨酸异常）。rbcR在大肠杆菌中作为与β-半乳糖苷酶N端区域融合的蛋白表达，导致rbcAB表达降低。因此，rbcR可能编码嗜硫小红卵菌中rbcAB表达的反式作用转录调节因子。
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rbcR [correction of rcbR], a gene coding for a member of the LysR family of transcriptional regulators, is located upstream of the expressed set of ribulose 1,5-bisphosphate carboxylase/oxygenase genes in the photosynthetic bacterium Chromatium vinosum.rbcR [rcbR的校正]是一种编码转录调节因子LysR家族成员的基因，位于光合细菌嗜硫小红卵菌中1,5-二磷酸核酮糖羧化酶/加氧酶基因表达集的上游。
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本文引用的文献
1
Nucleic acid sequence database IV.核酸序列数据库IV。
DNA. 1982;1(4):365-74. doi: 10.1089/dna.1982.1.365.
2
DNA structure and gene regulation.DNA结构与基因调控。
Prog Nucleic Acid Res Mol Biol. 1980;24:167-267. doi: 10.1016/s0079-6603(08)60674-1.
3
Biosynthetic mechanism of ribulose-1,5-bisphosphate carboxylase in the purple photosynthetic bacterium, Chromatium vinosum.紫色光合细菌嗜硫红假单胞菌中1,5-二磷酸核酮糖羧化酶的生物合成机制。
Arch Biochem Biophys. 1982 Apr 1;214(2):531-9. doi: 10.1016/0003-9861(82)90057-1.
4
Mechanism and control of transcription initiation in prokaryotes.原核生物转录起始的机制与调控
Annu Rev Biochem. 1985;54:171-204. doi: 10.1146/annurev.bi.54.070185.001131.
5
A large family of bacterial activator proteins.一大类细菌激活蛋白。
Proc Natl Acad Sci U S A. 1988 Sep;85(18):6602-6. doi: 10.1073/pnas.85.18.6602.
6
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Eur J Biochem. 1988 May 2;173(3):483-9. doi: 10.1111/j.1432-1033.1988.tb14024.x.
7
Molecular and cellular regulation of autotrophic carbon dioxide fixation in microorganisms.微生物中自养二氧化碳固定的分子与细胞调控
Microbiol Rev. 1988 Jun;52(2):155-89. doi: 10.1128/mr.52.2.155-189.1988.
8
Transcriptional activation at adjacent operators in the divergent-overlapping ilvY and ilvC promoters of Escherichia coli.大肠杆菌中反向重叠的ilvY和ilvC启动子相邻操纵基因处的转录激活。
J Mol Biol. 1988 Oct 5;203(3):643-63. doi: 10.1016/0022-2836(88)90199-4.
9
Nucleotide sequence of the Salmonella typhimurium metR gene and the metR-metE control region.鼠伤寒沙门氏菌metR基因及metR-metE调控区的核苷酸序列。
J Bacteriol. 1987 Sep;169(9):3932-7. doi: 10.1128/jb.169.9.3932-3937.1987.
10
Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli.阴沟肠杆菌临床分离株中诱导型头孢菌素酶的产生受一个已从大肠杆菌中缺失的调控基因控制。
EMBO J. 1986 Dec 20;5(13):3709-14. doi: 10.1002/j.1460-2075.1986.tb04704.x.
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