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[局限性银屑病治疗的新视角]

[New perspectives in treatment of bounded forms of psoriasis].

作者信息

Tsiskarashvili N V, Tsiskarashvili N I

出版信息

Georgian Med News. 2008 Nov(164):46-9.

PMID:19075342
Abstract

29 patients with bounded forms of psoriasis (18-52 years old 19 men and 10 women since several months to 15 years suffering from the named illness) once in the morning were treated with Daivobet (ointment for external application). By the 10-14th day after treatment full regress of skin fine eruptions and significant reduction of large nidus and intensity of peeling were observed in 20 patients. PASI index decreased by 60%, that allow use Daivonex ointment (1-2-times a day. For strengthening the effect duration of treatment was about 4-6 weeks. 19 patients continued 21-day treatment with Daivobet after decreasing of PASI index by more than 60% of initial level. In case of neurotic complaints, patients additionally underwent sessions of electronarcosis therapy. The course of medicinal electro narcosis consisted of 5-11 sessions with the frequency of procedures about 2-3-times a week. After this kind of therapy, 60% of patients had remission exceeded 4-6 months in comparison with the data recorded earlier in out-patients department cards. Thus, our observations confirm effectiveness of offered algorithm of psoriasis external therapy by means of Daivobet and Daivonex in combination with electronarcosis.

摘要

29例局限性银屑病患者(年龄18 - 52岁,男性19例,女性10例,患病数月至15年)每天早晨外用达力士倍他米松(Daivobet,外用软膏)进行治疗。治疗后第10 - 14天,20例患者皮肤细小皮疹完全消退,大的病灶显著缩小,脱屑强度明显降低。银屑病面积和严重程度指数(PASI)下降60%,这使得可使用得肤宝软膏(Daivonex,每天1 - 2次)。为增强治疗效果,疗程约4 - 6周。19例患者在PASI指数降至初始水平的60%以上后继续使用达力士倍他米松进行21天治疗。对于有神经症状的患者,额外接受电麻醉治疗。药物电麻醉疗程包括5 - 11次治疗,治疗频率约为每周2 - 3次。经过这种治疗后,与门诊病历中早期记录的数据相比,60%的患者缓解期超过4 - 6个月。因此,我们的观察结果证实了通过达力士倍他米松和得肤宝软膏联合电麻醉进行银屑病外用治疗方案的有效性。

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