Asakawa Y
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Curr Pharm Des. 2008;14(29):3067-88. doi: 10.2174/138161208786404272.
The bryophytes contain the Marchantiophyta (liverworts), Bryophyta (mosses) and Anthocerotophyta (hornworts) among which the Marchantiophyta contain cellular oil body and they produce a number of terpenoids, aromatic compounds and acetogenins, several of which show interesting biological activity such as allergenic contact dermatitis, insecticide, insect antifeedant, cytotoxic, piscicidal, muscle relaxing, plant growth regulatory, anti-HIV, DNA polymerase beta inhibitory, anti-obesity, neurotrophic, NO production inhibitory, antimicrobial and antifungal activities. The isolation and chemical structures of biologically active compounds and their total synthesis are reviewed.
苔藓植物包括地钱纲(叶苔)、藓纲(苔藓)和角苔纲(角苔),其中地钱纲含有细胞油体,它们能产生多种萜类化合物、芳香化合物和产乙酸素,其中一些具有有趣的生物活性,如变应性接触性皮炎、杀虫剂、昆虫拒食剂、细胞毒性、杀鱼剂、肌肉松弛、植物生长调节、抗HIV、DNA聚合酶β抑制、抗肥胖、神经营养、一氧化氮产生抑制、抗菌和抗真菌活性。本文综述了生物活性化合物的分离、化学结构及其全合成。