Taylor Eric
King's College London, Institute of Psychiatry, Department Child and Adolescent Psychiatry, London, UK.
J Child Psychol Psychiatry. 2009 Jan;50(1-2):126-32. doi: 10.1111/j.1469-7610.2008.01999.x.
Over the past 50 years the concept of attention deficit/hyperactivity disorder (ADHD) has developed from the notion of a specific form of brain dysfunction to that of a heterogeneous set of related behaviours. The great advances in genetics, neuroimaging and neuropsychiatry have made it one of the best understood forms of complex mental disturbance--but much remains to be done to translate understanding into practice. More effective treatment may come from identifying and treating more specific components of disorder and by a focus on identifying the factors determining course in the longer term so that they, as well as the core features of disorder, can become targets for intervention.
在过去的50年里,注意力缺陷多动障碍(ADHD)的概念已从一种特定形式的脑功能障碍发展为一组相关行为的异质性集合。遗传学、神经影像学和神经精神病学的巨大进展使其成为最容易理解的复杂精神障碍形式之一——但要将理解转化为实践,仍有许多工作要做。更有效的治疗可能来自于识别和治疗障碍中更具体的组成部分,并专注于识别长期决定病程的因素,以便这些因素以及障碍的核心特征都能成为干预的目标。