Yoon Ho Young, Kim Hyoung Il, Kim Choong Bai
Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2008 Nov;52(5):293-7.
BACKGROUND/AIMS: The aim of this study was to evaluate clinicopathologic differences between Type II and Type III groups that were classified by Siewert in cardia cancer.
A hundred forty-one patients who were diagnosed as gastric cardia cancer and underwent surgery between January 1990 and December 2006 by single surgeon at Department of Surgery, Yonsei University College of Medicine were included in this study. The Kaplan-Meier method and log rank test were used for survival analysis.
Barrett's adenocarcinoma was recognized in two patients so called type I. There were significant differences between type II and III in aspect of depth of invasion, Lauren's classification, and the number of retrieved lymph nodes in which cancer infiltrated. In type III, prognostic factors affecting survival were depth of invasion and nodal status in contrast to the no demonstrable prognostic factors existing in type II. However, there were no differences in recurrence and survival between two groups.
Several clinicopathologic differences exist between type II and III cardia cancer. In the future, further evaluation is needed regarding the classification and entities of the cardia cancer.
背景/目的：本研究旨在评估由Siewert对贲门癌进行分类的II型和III型组之间的临床病理差异。
本研究纳入了1990年1月至2006年12月期间在延世大学医学院外科由单一外科医生诊断为贲门癌并接受手术的141例患者。采用Kaplan-Meier法和对数秩检验进行生存分析。
在两名患者中识别出巴雷特腺癌，即所谓的I型。II型和III型在浸润深度、Lauren分类以及癌浸润的回收淋巴结数量方面存在显著差异。在III型中，影响生存的预后因素是浸润深度和淋巴结状态，而II型中不存在明显的预后因素。然而，两组之间在复发和生存方面没有差异。
II型和III型贲门癌之间存在若干临床病理差异。未来，需要对贲门癌的分类和实体进行进一步评估。
