Lim Jae-Young, Kim Kyoung-Eun, Choe Gheeyoung
Department of Rehabilitation, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Korea.
Am J Phys Med Rehabil. 2009 Feb;88(2):161-4. doi: 10.1097/PHM.0b013e318190b935.
We describe a 38-yr-old polio survivor with newly developed weakness from myotonic dystrophy. He suffered muscle atrophy and weakness in his legs as a result of poliomyelitis at the age of 3 yrs. After a stable interval of about 30 yrs, he felt new weakness and fatigue in his legs. Electromyography revealed generalized myotonic discharges, early recruitment, and findings of chronic denervation in his left leg. Genetic testing was consistent with myotonic dystrophy type 1. A biopsy from the right gastrocnemius revealed findings of both myotonic dystrophy and chronic denervation. This case report shows the importance of considering other uncommon conditions in the differential diagnoses of postpolio syndrome.
我们描述了一名38岁的脊髓灰质炎幸存者，其因强直性肌营养不良症出现了新的肌无力症状。他在3岁时因脊髓灰质炎导致腿部肌肉萎缩和无力。在大约30年的稳定期后，他感到腿部出现了新的无力和疲劳感。肌电图显示全身强直性放电、早期募集以及左腿慢性失神经支配的表现。基因检测结果与1型强直性肌营养不良症相符。右腓肠肌活检显示出强直性肌营养不良症和慢性失神经支配的表现。本病例报告显示了在脊髓灰质炎后综合征的鉴别诊断中考虑其他罕见病症的重要性。
