Gupta Ruchi S, Springston Elizabeth E, Weiss Kevin B
Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Children's Memorial Hospital, Chicago, Illinois, USA.
Curr Opin Pulm Med. 2009 Jan;15(1):72-8. doi: 10.1097/MCP.0b013e32831da911.
In spite of numerous efforts, asthma rates in the United States remain historically high and disparities persist among low-income and minority populations. This review assesses the current status of asthma inequities from the perspective of disease development, progression, and outcomes.
Recent findings highlight the complex and multifactorial nature of asthma. There is a clear line of emerging evidence suggestive of important hierarchical relationships between the predisposed or affected individual and his or her intrapersonal life, familial relationships, social networks, and broader community.
Approaches in basic, clinical, and translational asthma research must be modified to account for the social construct of race and to detangle complex interactions of contributing factors at and across the individual and community level. However, there are a number of obvious opportunities to dramatically reduce asthma disparities at hand.
尽管付出了诸多努力,但美国的哮喘发病率仍处于历史高位,低收入和少数族裔人群之间的差距依然存在。本综述从疾病发展、进展和结局的角度评估哮喘不平等的现状。
最新发现凸显了哮喘的复杂性和多因素性质。有一系列新出现的证据表明,易患或患病个体与其个人生活、家庭关系、社交网络及更广泛社区之间存在重要的层级关系。
基础、临床和转化性哮喘研究的方法必须加以改进,以考虑种族的社会建构,并理清个体及社区层面促成因素的复杂相互作用。然而,目前有许多明显的机会可大幅减少哮喘差距。