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Epi-LASIK 中“掀瓣”与“免掀瓣”技术治疗中低度近视的对比评估。

Comparative evaluation of 'flap on' and 'flap off' techniques of Epi-LASIK in low-to-moderate myopia.

机构信息

Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Eye (Lond). 2009 Sep;23(9):1786-9. doi: 10.1038/eye.2008.367. Epub 2008 Dec 12.

Abstract

PURPOSE

Comparative evaluation of 'flap on' and 'flap off' techniques of Epi-LASIK in low-to-moderate myopia.

METHODS

Sixteen eyes of eight consecutive patients with myopia < or = 6 D were selected for this prospective, randomized, comparative, interventional case series. Epi-LASIK surgery was performed in all eyes. In one eye of each patient, the epithelial flap was retained after excimer laser ablation (flap on). In the fellow eye, the epithelial flap was discarded (flap off) after ablation. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), spherical equivalent (SEQ), postoperative pain score, time to epithelization, and corneal haze were recorded on postoperative visits.

RESULTS

The mean preoperative SEQ in the two groups was -3.61+/-1.32 D (flap on) and -3.49+/-1.86 D (flap off; P=0.752). The mean follow-up period was 8.5+/-4.9 months. The mean pain score was comparable on all postoperative days except the second postoperative day when the group with flap off had a lesser mean pain score (P=0.053).Time for epithelial healing was 3.63+/-0.52 days in cases with flap off and 4.13+/-0.64 days in cases with flap on (P=0.113). Eyes with flap off had a better UCVA on the first postoperative day (0.19+/-0.11 logMAR) compared with eyes with flap on (0.41+/-0.28 logMAR; P=0.032). There was no significant difference in UCVA, BSCVA, SEQ, contrast sensitivity, corneal haze, and higher order aberrations at any other postoperative visit.

CONCLUSIONS

There is no difference between flap on and flap off techniques of Epi-LASIK with regards to overall outcome of surgery.

摘要

目的

比较 Epi-LASIK 中“ flap on”和“ flap off”技术在中低度近视中的效果。

方法

连续 8 例 16 只眼近视患者(<或=6D)参与了这项前瞻性、随机、对照、干预性病例系列研究。所有眼均行 Epi-LASIK 手术。在每位患者的一只眼中,在准分子激光消融后保留上皮瓣( flap on)。在对侧眼,在消融后丢弃上皮瓣( flap off)。术后随访时记录未矫正视力(UCVA)、最佳矫正视力(BSCVA)、等效球镜(SEQ)、术后疼痛评分、上皮愈合时间和角膜混浊情况。

结果

两组术前平均 SEQ 分别为-3.61+/-1.32 D( flap on)和-3.49+/-1.86 D( flap off; P=0.752)。平均随访时间为 8.5+/-4.9 个月。除术后第 2 天外,两组在所有术后日的疼痛评分均相当( flap off 组的平均疼痛评分较低,P=0.053)。上皮愈合时间在 flap off 组为 3.63+/-0.52 天,在 flap on 组为 4.13+/-0.64 天( P=0.113)。 flap off 组术后第 1 天的 UCVA 更好(0.19+/-0.11 logMAR),而 flap on 组为 0.41+/-0.28 logMAR( P=0.032)。在任何其他术后随访时,UCVA、BSCVA、SEQ、对比敏感度、角膜混浊和高阶像差均无显著差异。

结论

在 Epi-LASIK 手术的整体效果方面, flap on 和 flap off 技术没有差异。

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