Department of Ophthalmology, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.
Graefes Arch Clin Exp Ophthalmol. 2013 Apr;251(4):1175-83. doi: 10.1007/s00417-012-2181-7. Epub 2012 Oct 25.
Laser in situ keratomileusis (LASIK) is superior to surface ablation techniques (SAT) such as alcohol photorefractive keratectomy (APRK) or Epi-LASIK (EpiK) in terms of visual recovery and postoperative pain. This study compares subjective symptoms and visual recovery of two different SATs with LASIK.
One hundred and twenty seven patients were operated using one of the three techniques. Patients filled out a questionnaire describing symptoms assessing subjective visual recovery on a linear scale from 'not functioning' to 'full visual function' and pain on a linear scale from 'no pain' to 'severe daily pain'. Subjective symptoms such as halos, double vision, low night vision, reduced contrast and dry eyes were also evaluated.
Visual recovery was faster and discomfort symptoms less pronounced with the LASIK than with surface ablation procedures. More pain was reported after APRK than after EpiK (flap-off technique) in the early postoperative period, with a maximum of pain on postoperative days 3-4. Subjective visual recovery showed no statistically significant difference between the two surface ablation procedures. Halos, double vision, low night vision, reduced contrast and dry eyes were more extensively reported by the EpiK than the APRK group and were less pronounced in the LASIK than in the SAT group.
Our study does not uniformly support the previously published favourable results of EpiK compared to APRK with regard to subjective recovery of vision and postoperative pain.
激光原位角膜磨镶术(LASIK)在视觉恢复和术后疼痛方面优于表面消融技术(SAT),如酒精光折射性角膜切削术(APRK)或 Epi-LASIK(EpiK)。本研究比较了 LASIK 与两种不同 SAT 术后的主观症状和视觉恢复。
127 例患者分别采用三种技术中的一种进行手术。患者填写一份问卷,描述症状,以线性尺度从“无功能”到“完全视觉功能”评估主观视觉恢复,以线性尺度从“无疼痛”到“严重日常疼痛”评估疼痛。还评估了光晕、复视、夜视能力下降、对比度降低和干眼症等主观症状。
LASIK 比表面消融术恢复更快,不适症状也较轻。APRK 术后早期的疼痛比 EpiK(瓣下技术)更严重,术后 3-4 天疼痛达到高峰。两种表面消融术之间的主观视觉恢复没有统计学上的显著差异。EpiK 组比 APRK 组报告的光晕、复视、夜视能力下降、对比度降低和干眼症更为广泛,LASIK 组比 SAT 组的这些症状更为轻微。
本研究并不完全支持先前发表的 EpiK 比 APRK 在视觉恢复和术后疼痛方面更有优势的结果。