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Hyaluronic acid-based nanogel-drug conjugates with enhanced anticancer activity designed for the targeting of CD44-positive and drug-resistant tumors.基于透明质酸的纳米凝胶-药物偶联物，具有增强的抗癌活性，旨在针对 CD44 阳性和耐药肿瘤进行靶向治疗。
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Nanogels as pharmaceutical carriers: finite networks of infinite capabilities.作为药物载体的纳米凝胶：具有无限能力的有限网络。
Angew Chem Int Ed Engl. 2009;48(30):5418-29. doi: 10.1002/anie.200900441.
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Polymeric nanogel formulations of nucleoside analogs.核苷类似物的聚合物纳米凝胶制剂
Expert Opin Drug Deliv. 2007 Jan;4(1):5-17. doi: 10.1517/17425247.4.1.5.

本文引用的文献

1
Comparison of nanogel drug carriers and their formulations with nucleoside 5'-triphosphates.纳米凝胶药物载体及其制剂与核苷5'-三磷酸的比较。
Pharm Res. 2006 May;23(5):920-30. doi: 10.1007/s11095-006-9788-5. Epub 2006 May 2.
2
Cross-linked polymeric nanogel formulations of 5'-triphosphates of nucleoside analogues: role of the cellular membrane in drug release.核苷类似物5'-三磷酸的交联聚合物纳米凝胶制剂：细胞膜在药物释放中的作用。
Mol Pharm. 2005 Nov-Dec;2(6):449-61. doi: 10.1021/mp0500364.
3
Polyplex Nanogel formulations for drug delivery of cytotoxic nucleoside analogs.用于细胞毒性核苷类似物药物递送的聚复合物纳米凝胶制剂。
J Control Release. 2005 Sep 20;107(1):143-57. doi: 10.1016/j.jconrel.2005.06.002.
4
Nanogels for oligonucleotide delivery to the brain.用于将寡核苷酸递送至大脑的纳米凝胶。
Bioconjug Chem. 2004 Jan-Feb;15(1):50-60. doi: 10.1021/bc034164r.
5
Cytotoxic and antitumor activities of doxorubicin conjugates with the epidermal growth factor and its receptor-binding fragment.阿霉素与表皮生长因子及其受体结合片段的偶联物的细胞毒性和抗肿瘤活性。
J Drug Target. 2002 Nov;10(7):567-71. doi: 10.1080/1061186021000038058.
6
Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells.用于药物递送的纳米阳离子水凝胶：制备、性质及其与细胞的相互作用
Adv Drug Deliv Rev. 2002 Jan 17;54(1):135-47. doi: 10.1016/s0169-409x(01)00245-9.
7
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine.使用可逆交联的低分子量聚乙烯亚胺进行高效基因转移。
Bioconjug Chem. 2001 Nov-Dec;12(6):989-94. doi: 10.1021/bc0100455.

Chemical engineering of nanogel drug carriers: increased bioavailability and decreased cytotoxicity.

作者信息

Vinogradov Serguei V, Kohli Ekta, Zeman Arin, Kabanov Alexander V

机构信息

Center for Drug Delivery and Nanomedicine and Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, NE68198-5830.

出版信息

Polymer Prepr. 2006;47(2):27-28.

PMID:19079755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2601575/
Abstract
摘要