Frieder Ariela, Dunlop Anne L, Culpepper Larry, Bernstein Peter S
Department of Psychiatry, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY 10467, USA.
Am J Obstet Gynecol. 2008 Dec;199(6 Suppl 2):S328-32. doi: 10.1016/j.ajog.2008.09.001.
For a substantial proportion of women, pregnancy can be complicated by the occurrence or reoccurrence of a psychiatric condition. Psychiatric disorders during pregnancy are associated with poor obstetric outcomes, higher risk of postpartum psychiatric illness, increased rates of substance abuse, lower participation in prenatal care, and adverse infant and family outcomes. As part of preconception care, providers should be vigilant and screen for psychiatric disorders among women of reproductive age, as the detection and appropriate management of these conditions can reduce the occurrence of adverse pregnancy and family outcomes. This manuscript reviews the treatment options and the risks and benefits of discontinuing, changing, or continuing psychotropic medications for women of reproductive age with common psychiatric disorders (depression and anxiety disorders, bipolar disorder, and schizophrenia) and offers recommendations for preconception care.
对于相当一部分女性来说,怀孕可能会因精神疾病的发生或复发而变得复杂。孕期精神障碍与不良产科结局、产后精神疾病的高风险、药物滥用率增加、产前护理参与度降低以及不良的婴儿和家庭结局相关。作为孕前护理的一部分,医疗服务提供者应保持警惕,对育龄女性进行精神障碍筛查,因为对这些疾病的检测和适当管理可以减少不良妊娠和家庭结局的发生。本文综述了患有常见精神障碍(抑郁症和焦虑症、双相情感障碍和精神分裂症)的育龄女性停用、更换或继续使用精神药物的治疗选择以及风险和益处,并为孕前护理提供建议。