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患有严重精神疾病的女性在进行妊娠护理时的生殖计划、维生素知识和使用情况,以及生活方式风险。

Reproductive planning, vitamin knowledge and use, and lifestyle risks of women attending pregnancy care with a severe mental illness.

机构信息

Medical School, Division of General practice, The University of Western Australia, Crawley, WA, Australia.

Department of Obstetrics, Women and Newborn Health Service, Subiaco, WA, Australia.

出版信息

Scand J Prim Health Care. 2021 Mar;39(1):60-66. doi: 10.1080/02813432.2021.1882081. Epub 2021 Feb 11.

Abstract

OBJECTIVE

Women with severe mental illnesses are a vulnerable population and little is known about their reproductive planning needs. The aim of our study was to describe rates of unintended pregnancies, postpartum contraception, identify use and knowledge of prenatal/pregnancy vitamins and identify modifiable lifestyle risks.

DESIGN

Mixed methods study incorporating a cross-sectional survey and prospective pregnancy data collection.

SETTING

A multidisciplinary antenatal clinic in Australia.

METHOD

Thirty-eight pregnant women with severe mental illnesses: schizophrenia, schizoaffective, bipolar and severe post-traumatic stress disorder.

MAIN OUTCOME MEASURES

Unintended pregnancy rates, immediate postpartum contraception, use of prenatal and pregnancy vitamins and knowledge sources, obesity, and use and cessation rates for smoking, and substances, and comorbid medical conditions.

RESULTS

Overall 42% of women had unintended pregnancy, with those with schizophrenia at most risk (56%). A long acting reversible contraception was inserted in 5 women (13%), with 45% having no immediate contraception prescribed prior to postnatal discharge. Women's main source of vitamin supplementation for pregnancy was from general practitioners. Prenatal folic acid use occurred in 37%, with rates differing for those with a diagnosis of bipolar disorder (52%) and schizophrenia (25%). Vitamin deficiencies occurred in pregnancy, with iron deficiency (ferritin <30 ng/mL) ( = 27, 73%) the most frequent. Overall 21% of women smoked cigarettes and 35% were obese.

DISCUSSION

Addressing gaps in use of effective contraception, proactive reproductive planning and lifestyle management may improve outcomes for women with mental illnesses and their babies.Key pointsWomen with severe mental illnesses have complex health needs that require targeted reproductive counselling. This study adds to what is known by highlighting that:•Women with schizophrenia appear more likely to have unintended pregnancy.•Prenatal counselling for women with severe mental disorders should include recognition and optimisation of management for the high rates of pre-existing medical comorbidities, obesity and elevated nicotine and substance use.•Many women with severe mental illness need increased doses (5 mg) of prenatal folic acid due to psychotropic medication risk and obesity, as well as treatment for high rates of iron and vitamin D deficiency in pregnancy.

摘要

目的

患有严重精神疾病的女性是一个弱势群体,她们的生殖计划需求知之甚少。本研究旨在描述意外怀孕率、产后避孕措施,识别产前/孕期维生素的使用和知识来源,并确定可改变的生活方式风险。

设计

结合横断面调查和前瞻性妊娠数据收集的混合方法研究。

地点

澳大利亚的一个多学科产前诊所。

方法

38 名患有严重精神疾病的孕妇:精神分裂症、分裂情感障碍、双相情感障碍和严重创伤后应激障碍。

主要结果测量

意外怀孕率、产后立即避孕措施、产前和孕期维生素的使用和知识来源、肥胖以及吸烟和物质的使用和停用率,以及合并的医疗状况。

结果

总体而言,42%的女性怀孕意外,其中精神分裂症患者风险最高(56%)。5 名女性(13%)插入了长效可逆避孕措施,45%的女性在产后出院前没有立即开避孕药。女性补充孕期维生素的主要来源是全科医生。产前叶酸的使用发生在 37%的女性中,其中被诊断为双相情感障碍(52%)和精神分裂症(25%)的女性发生率更高。怀孕期间发生维生素缺乏症,铁缺乏(血清铁蛋白<30ng/ml)( = 27,73%)最常见。总体而言,21%的女性吸烟,35%的女性肥胖。

讨论

解决有效避孕措施使用方面的差距、主动生殖计划和生活方式管理可能会改善患有精神疾病的女性及其婴儿的结局。

关键点

患有严重精神疾病的女性有复杂的健康需求,需要有针对性的生殖咨询。本研究通过强调以下几点,增加了我们对这方面的了解:

  • 精神分裂症女性似乎更有可能意外怀孕。

  • 对患有严重精神障碍的女性进行产前咨询时,应包括识别和优化管理,以解决高发的现有合并疾病、肥胖、尼古丁和物质使用增加的问题。

  • 由于精神药物风险和肥胖,许多患有严重精神疾病的女性需要增加(5mg)产前叶酸剂量,以及治疗妊娠期间铁和维生素 D 缺乏的问题。

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