Douglas Crystal C, Lawrence Jeannine C, Bush Nikki C, Oster Robert A, Gower Barbara A, Darnell Betty E
Division of Physiology and Metabolism, Department of Nutrition Sciences, The University of Alabama at Birmingham, 1675 University Boulevard, Birmingham, AL 35294-3360, USA.
Nutr Res. 2007 Apr;27(4):194-199. doi: 10.1016/j.nutres.2007.01.016.
The objective of this study was to assess the effects of weight history status and ethnicity on the ability of the Harris Benedict (HB) formula to: 1) predict measured resting energy expenditure (REE), and, 2) accurately estimate energy needs over a 2-week test period. Subjects were never-overweight (BMI </= 25 kg/m(2), n=47), overweight (BMI 27-30 kg/m(2), n=170), and weight-reduced (BMI </= 25 kg/m(2), n=51) healthy, adult African-American (AA) and Caucasian (C) women. Food was provided for 2 weeks at an energy level calculated using the HB formula multiplied by a 1.35 activity factor. After 2 weeks, weight, REE (by indirect calorimetry), and body composition (by dual-energy X-ray absorptiometry) were assessed. Data were analyzed using 2-way ANOVA at p<0.05 significance. The HB formula overestimated REE 1) in each weight history group (by 160 +/-125 kcals among never-overweight, 295 +/-189 kcal among overweight, and 105 +/-135 among weight-reduced) such that there was a group effect on overestimation (P<0.001) and 2) between ethnicities, with a greater overestimation in AA vs. C (P<0.001). There was a significant effect of weight history group on weight change (P<0.001) over 2-weeks, such that weight-reduced women gained more weight than the other two groups (P<0.05). In conclusion, the ability of the HB formula to estimate REE differed with weight history status and ethnicity. The accuracy of the HB formula to predict dietary energy needs was affected by weight history status. These results suggest that formulas used to calculate energy needs should take into account weight history and ethnicity.
本研究的目的是评估体重历史状况和种族对哈里斯-本尼迪克特（HB）公式在以下两方面能力的影响：1）预测实测静息能量消耗（REE），以及2）在为期2周的测试期内准确估算能量需求。研究对象为健康的成年非裔美国（AA）和白人（C）女性，分为体重从未超重组（BMI≤25kg/m²，n = 47）、超重组（BMI 27 - 30kg/m²，n = 170）和体重减轻组（BMI≤25kg/m²，n = 51）。按照HB公式乘以1.35的活动系数计算出能量水平，为研究对象提供2周的食物。2周后，评估体重、REE（通过间接测热法）和身体成分（通过双能X线吸收法）。采用双向方差分析对数据进行分析，显著性水平设定为p<0.05。HB公式高估了REE：1）在每个体重历史组中（从未超重组高估160±125千卡，超重组高估295±189千卡，体重减轻组高估105±135千卡），因此在高估方面存在组间效应（P<0.001）；2）在不同种族之间，AA族比C族高估更明显（P<0.001）。体重历史组对2周内的体重变化有显著影响（P<0.001），体重减轻组女性比其他两组体重增加更多（P<0.05）。总之，HB公式估算REE的能力因体重历史状况和种族而异。HB公式预测膳食能量需求的准确性受体重历史状况影响。这些结果表明，用于计算能量需求的公式应考虑体重历史和种族因素。
