Nitroxyl radicals as low toxic spin-labels for non-invasive magnetic resonance imaging of blood-brain barrier permeability for conventional therapeutics.
作者信息
Zhelev Zhivko, Bakalova Rumiana, Aoki Ichio, Matsumoto Ken-Ichiro, Gadjeva Veselina, Anzai Kazunori, Kanno Iwao
机构信息
Department of Biophysics, Molecular Imaging Center, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan.
出版信息
Chem Commun (Camb). 2009 Jan 7(1):53-5. doi: 10.1039/b816878d. Epub 2008 Nov 13.
DOI:10.1039/b816878d
PMID:19081996
Abstract
The present study describes a novel non-radioactive methodology for in vivo non-invasive, real-time imaging of blood-brain barrier (BBB) permeability for conventional drugs, using nitroxyl radicals as spin-labels and magnetic resonance imaging (MRI).
摘要
Zotero 插件