Campbell-Verduyn Lachlan, Elsinga Philip H, Mirfeizi Leila, Dierckx Rudi A, Feringa Ben L
Stratingh Institute for Chemistry, University of Groningen, Groningen, The Netherlands.
Org Biomol Chem. 2008 Oct 7;6(19):3461-3. doi: 10.1039/b812403e. Epub 2008 Aug 13.
Arynes formed through fluoride-promoted ortho-elimination of o-(trimethylsilyl)aryl triflates can undergo [3 + 2] cycloaddition with various azides to form substituted benzotriazoles. The rapid reaction times and mild conditions make this an attractive variation of the classical 'click' reaction of azides and alkynes.
通过氟化物促进邻位（三甲基硅基）芳基三氟甲磺酸酯的邻位消除形成的芳炔可以与各种叠氮化物发生[3 + 2]环加成反应，生成取代的苯并三唑。快速的反应时间和温和的条件使其成为叠氮化物与炔烃经典“点击”反应的一种有吸引力的变体。
