Matsui Jun, Takayose Megumi, Akamatsu Kensuke, Nawafune Hidemi, Tamaki Katsuyuki, Sugimoto Naoki
Frontier Institute for Biomolecular Engineering Research, Konan University, 8-9-1 Okamoto, Higashinada-ku, Kobe 658-8501, Japan.
Analyst. 2009 Jan;134(1):80-6. doi: 10.1039/b803350a. Epub 2008 Oct 20.
A surface plasmon resonance (SPR) sensor highly sensitive and selective for the herbicide atrazine was composed by immobilizing atrazine-imprinted polymer with gold nanoparticles on a gold thin film as a sensor chip. In the detection, the atrazine-imprinted polymer was expected to work as synthetic receptor for selectively capturing atrazine in organic solvent, and the gold nanoparticles were expected to exhibit a coupling effect with the gold thin film to enhance the local electromagnetic field between the nanoparticles and the gold film, making the sensor chip highly sensitive for changes in microenvironmental polarity. Thus, a combination of the atrazine-imprinted polymer and gold nanoparticles enabled us to compose an SPR sensor demonstrating the detection of 5 pM atrazine in acetonitrile.
一种对除草剂阿特拉津具有高灵敏度和选择性的表面等离子体共振（SPR）传感器，是通过将阿特拉津印迹聚合物与金纳米颗粒固定在金薄膜上作为传感器芯片而构成的。在检测过程中，阿特拉津印迹聚合物有望作为合成受体在有机溶剂中选择性捕获阿特拉津，而金纳米颗粒有望与金薄膜表现出耦合效应，增强纳米颗粒与金膜之间的局部电磁场，使传感器芯片对微环境极性变化具有高灵敏度。因此，阿特拉津印迹聚合物和金纳米颗粒的结合使我们能够构建一种SPR传感器，该传感器能够检测乙腈中5 pM的阿特拉津。
