卡氏枝孢瓶霉：巴西里约热内卢州着色芽生菌病的罕见病原体。
Cladophialophora carrionii: a rare agent of chromoblastomycosis in Rio de Janeiro State, Brazil.
作者信息
Mouchalouat Marcelle de F, Galhardo Maria Clara G, Fialho Paulo Cezar Monteiro, Coelho Janice Mery C de Oliveira, Zancopé-Oliveira Rosely Maria, Valle Antonio Carlos F do
机构信息
Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
出版信息
Rev Inst Med Trop Sao Paulo. 2008 Nov-Dec;50(6):351-3. doi: 10.1590/s0036-46652008000600008.
A 73 year-old male farm laborer from a rural area presented a 15 year history of extensive tumoral lesions over his left leg. Histological studies of skin biopsy showed pseudoepitheliomatous hyperplasia and granulomatous chronic inflammatory process with muriform cells, confirming chromoblastomycosis (CBM). Cladophialophora carrionii was isolated in culture. Treatment with itraconazole 400 mg/day for 12 months resulted in complete remission of lesions. As far we aware, this is the first case report of CBM caused by Cladophialophora carrionii in Rio de Janeiro State, Brazil.
一名来自农村地区的73岁男性农场工人，左腿出现广泛肿瘤性病变已有15年病史。皮肤活检的组织学研究显示假上皮瘤样增生以及伴有砖形细胞的肉芽肿性慢性炎症过程，确诊为着色芽生菌病（CBM）。培养分离出了卡氏枝孢霉。给予伊曲康唑400毫克/天治疗12个月后，病变完全缓解。据我们所知，这是巴西里约热内卢州首例由卡氏枝孢霉引起的着色芽生菌病病例报告。
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