Ward L C, Czerniec S, Kilbreath S L
School of Molecular and Microbial Sciences, University of Queensland, St Lucia, Brisbane, QLD 4072, Australia.
Breast Cancer Res Treat. 2009 Oct;117(3):541-7. doi: 10.1007/s10549-008-0258-0. Epub 2008 Dec 11.
The aim was to make bioimpedance spectroscopy (BIS) quantitative for assessment of lymphoedema. Apparent resistivity coefficients were determined for the intra- and extracellular water of arms in a control cohort of women (n = 66). These coefficients were used to predict water volumes in the arms of women with lymphoedema (n = 23) and a separate control group without lymphoedema (n = 13) and to compare these with total arm size measured by perometry. Total arm volume was highly correlated (r = 0.80-0.90) with arm fluid volumes predicted by BIS and the proportional increase in arm size predicted by BIS was not significantly different to that measured by perometry. BIS predicted that the increased volume in the women with lymphoedema was predominantly (60%) due to increase in extracellular fluid. BIS is capable of quantifying the volume increase in limb size seen in lymphoedema.
目的是使生物电阻抗光谱法（BIS）能够定量评估淋巴水肿。在一组女性对照队列（n = 66）中测定了手臂细胞内和细胞外水的表观电阻率系数。这些系数用于预测淋巴水肿女性（n = 23）和另一组无淋巴水肿的对照组女性（n = 13）手臂中的水量，并将其与通过周长测量法测得的手臂总尺寸进行比较。手臂总体积与BIS预测的手臂液体体积高度相关（r = 0.80 - 0.90），且BIS预测的手臂尺寸的比例增加与周长测量法测得的结果无显著差异。BIS预测，淋巴水肿女性的体积增加主要（60%）是由于细胞外液增加所致。BIS能够定量评估淋巴水肿中肢体尺寸的体积增加。
