Tewari Nilajana, Gill Peter G, Bochner Melissa A, Kollias James
Breast Unit and Women's Health Centre, Royal Adelaide Hospital Cancer Centre.
ANZ J Surg. 2008 Oct;78(10):889-93. doi: 10.1111/j.1445-2197.2008.04686.x.
The Royal Australasian College of Surgeons Sentinel Node versus Axillary Clearance trial is a randomized controlled trial comparing sentinel node biopsy with axillary clearance in breast cancer patients. Primary study end-points include arm volume differences with time, which may indicate the development of lymphoedema. The RACS SNAC trial uses circumferential arm measurements in the estimation of arm volume. This study aimed to assess the accuracy of circumferential volume estimation in comparison with water displacement.
Eighty-seven women attending the breast clinic at the Women's Health Centre, Royal Adelaide Hospital, were assessed by volumetric and circumferential arm measurements. Correlations between volume estimations and measurements were made, taking into account the width of measuring tape and body mass index.
There was a highly significant correlation between circumferential and volumetric arm measurements (Pearson's correlation coefficient = 0.92, P < 0.0001), especially when using the narrow measuring tape. Correlation was best in the overweight BMI group (Pearson's correlation coefficient = 0.94. P < 0.0001) and worst in the obese group (Pearson's correlation coefficient = 0.79, P < 0.0001) but all relationships were statistically significant.
Using a narrow tape, circumferential arm measurement is an appropriate method for assessing arm volume in the SNAC trial.
澳大利亚皇家外科学院前哨淋巴结与腋窝清扫试验是一项随机对照试验，比较乳腺癌患者前哨淋巴结活检与腋窝清扫。主要研究终点包括手臂体积随时间的差异，这可能提示淋巴水肿的发生。RACS SNAC试验采用手臂周径测量来估计手臂体积。本研究旨在评估与排水法相比，周径体积估计的准确性。
对87名在皇家阿德莱德医院妇女健康中心乳腺门诊就诊的女性进行了手臂体积和周径测量评估。考虑到卷尺宽度和体重指数，对体积估计值与测量值之间进行了相关性分析。
手臂周径测量与体积测量之间存在高度显著的相关性（皮尔逊相关系数=0.92，P<0.0001），尤其是使用窄卷尺时。超重BMI组的相关性最佳（皮尔逊相关系数=0.94，P<0.0001），肥胖组最差（皮尔逊相关系数=0.79，P<0.0001），但所有关系均具有统计学意义。
在SNAC试验中，使用窄卷尺进行手臂周径测量是评估手臂体积的一种合适方法。
