HE Rong-rong, ZHOU Huai-jun
Gulou Medical College of Integrative Chinese and Western Medicine, The No.1 Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing (210029), China.
Chin J Integr Med. 2008 Dec;14(4):312-6. doi: 10.1007/s11655-008-0312-0. Epub 2008 Dec 12.
It has been found in recent years that Artesunate (Art), a water soluble derivative of arteannuin, mainly previously used for its anti-malarial activity, has some other effects, e.g. it could act as an anti-tumor agent by way of inducing cell apoptosis, antagonizing angiogenesis, reversing immunosuppression of tumor cells, etc. More and more attention is being paid to the anti-tumor effects of Art. Such progress is reviewed in this paper.
近年来发现，青蒿琥酯（Art）是青蒿素的水溶性衍生物，以前主要因其抗疟活性而被使用，它还有其他一些作用，例如它可以通过诱导细胞凋亡、拮抗血管生成、逆转肿瘤细胞的免疫抑制等方式发挥抗肿瘤作用。青蒿琥酯的抗肿瘤作用越来越受到关注。本文对这方面的进展进行综述。
