Liew Steven, Dart Andrea
Aesthet Surg J. 2008 May-Jun;28(3):251-7. doi: 10.1016/j.asj.2008.03.003.
The use of botulinum toxin in aesthetic reshaping of the mandibular angle has been well established in East Asian populations. This has not previously been investigated in Western populations.
Our objective was to determine the efficacy of botulinum toxin injections in aesthetic reshaping of the lower face in Western populations and compare it to that in East Asian populations.
Thirty-four Western patients (study group) had their masseteric muscles injected with botulinum toxin with an initial dose of 25 to 30 units on each side. This was compared to 48 East Asian patients (control group) who received an initial dose of 40 units on each side.
All patients achieved aesthetic improvement of the shape of their lower face, with an additional improvement in functional outcome attributed to bruxism in Western patients. There were few complications. The therapeutic dose for the Western population was lower than that for East Asian patients. In the Western population, aesthetic improvement lasted from 9 to 12 months, while the functional improvement from bruxism lasted for 6 to 7 months.
Botulinum toxin is effective in improving the aesthetic appearance of the lower face and the functional outcome in Western patients with masseteric hypertrophy.
肉毒杆菌毒素用于下颌角美学重塑在东亚人群中已得到充分证实。此前尚未在西方人群中进行过研究。
我们的目的是确定肉毒杆菌毒素注射对西方人群下面部美学重塑的疗效,并将其与东亚人群进行比较。
34名西方患者(研究组)接受肉毒杆菌毒素注射咬肌,初始剂量为每侧25至30单位。将其与48名东亚患者(对照组)进行比较,后者每侧接受40单位的初始剂量。
所有患者下面部形状均有美学改善,西方患者因磨牙症导致的功能结果也有额外改善。并发症很少。西方人群的治疗剂量低于东亚患者。在西方人群中,美学改善持续9至12个月,而磨牙症导致的功能改善持续6至7个月。
肉毒杆菌毒素对改善西方咬肌肥大患者的下面部美学外观和功能结果有效。