Marino Miguel, Sala Andrea, Corach Daniel
Servicio de Huellas Digitales Genéticas and Cátedra de Genética y Biología Molecular, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Argentina.
Forensic Sci Int Genet. 2007 Jun;1(2):129-33. doi: 10.1016/j.fsigen.2007.01.013. Epub 2007 Mar 7.
We investigated nine Y-STRs on 1136 unrelated males from 10 provinces and three aboriginal tribes of Argentina. The urban populations depicted 654 different haplotypes (66%) and a haplotype diversity (HD) value of 0.9967. Meanwhile, the Amerindian groups ranged from 20 to 26 different haplotypes (62.5-38.2%) and the HD values from 0.8635 to 0.9586. By AMOVA it was determined a remarkable homogeneous haplotype distribution, nevertheless a certain degree of genetic substructure was detected in the North region, in particular in Salta population. Genetic distance allowed to identify three clusters one of them included Salta population and the Amerindian tribes. The results presented herein showed the impact of the European male genetic contribution on the aboriginal gene pool that can be, at present, assessed by analyzing the nowadays extant population.
我们对来自阿根廷10个省份和3个原住民部落的1136名无关男性进行了9个Y染色体短串联重复序列（Y-STR）的研究。城市人口呈现出654种不同的单倍型（66%），单倍型多样性（HD）值为0.9967。同时，美洲印第安人群体的单倍型数量在20至26种之间（62.5 - 38.2%），HD值在0.8635至0.9586之间。通过分子方差分析（AMOVA）确定了单倍型分布具有显著的同质性，然而在北部地区，特别是萨尔塔人群中检测到了一定程度的遗传亚结构。遗传距离分析允许识别出三个聚类，其中一个聚类包括萨尔塔人群和美洲印第安部落。本文呈现的结果显示了欧洲男性基因贡献对原住民基因库的影响，目前可以通过分析现存人群来评估这种影响。
