Soltyszewski Ireneusz, Plocienniczak Andrzej, Fabricius Hans Ake, Kornienko Igor, Vodolazhsky Dmitrij, Parson Walther, Hradil Roman, Schmitter Hermann, Ivanov Pavel, Kuzniar Piotr, Malyarchuk Boris A, Grzybowski Tomasz, Woźniak Marcin, Henke Jurgen, Henke Lotte, Olkhovets Sergiv, Voitenko Vladimir, Lagus Vita, Ficek Andrej, Minárik Gabriel, de Knijff Peter, Rebała Krzysztof, Wysocka Joanna, Kapińska Ewa, Cybulska Lidia, Mikulich Alexei I, Tsybovsky Iosif S, Szczerkowska Zofia, Krajewski Paweł, Ploski Rafał
University of Varmia and Mazury, Department of Criminalistics and Forensic Medicine, Olsztyn, Poland.
Forensic Sci Int Genet. 2008 Jun;2(3):205-11. doi: 10.1016/j.fsigen.2008.02.003. Epub 2008 Apr 18.
The purpose of this study was to evaluate the homogeneity of Polish populations with respect to STRs chosen as core markers of the Polish Forensic National DNA Intelligence Database, and to provide reference allele frequencies and to explore the genetic interrelationship between Poland and neighboring countries. The allele frequency distribution of 10 STRs included in the SGMplus kit was analyzed among 2176 unrelated individuals from 6 regional Polish populations and among 4321 individuals from Germany (three samples), Austria, The Netherlands, Sweden, Czech Republic, Slovakia, Belarus, Ukraine and the Russian Federation (six samples). The statistical approach consisted of AMOVA, calculation of pairwise Rst values and analysis by multidimensional scaling. We found homogeneity of present day Poland and consistent differences between Polish and German populations which contrasted with relative similarities between Russian and German populations. These discrepancies between genetic and geographic distances were confirmed by analysis of an independent data set on Y chromosome STRs. Migrations of Goths, Viking influences, German settlements in the region of Volga river and/or forced population resettlements and other events related to World War II are the historic events which might have caused these finding.
本研究的目的是评估波兰人群在被选为波兰法医国家DNA情报数据库核心标记的STR方面的同质性，提供参考等位基因频率，并探索波兰与邻国之间的遗传相互关系。在来自波兰6个地区人群的2176名无关个体以及来自德国（三个样本）、奥地利、荷兰、瑞典、捷克共和国、斯洛伐克、白俄罗斯、乌克兰和俄罗斯联邦（六个样本）的4321名个体中，分析了SGMplus试剂盒中包含的10个STR的等位基因频率分布。统计方法包括分子变异分析（AMOVA）、成对Rst值的计算以及多维标度分析。我们发现当今波兰人群具有同质性，波兰和德国人群之间存在一致的差异，这与俄罗斯和德国人群之间的相对相似性形成对比。Y染色体STR独立数据集的分析证实了遗传距离和地理距离之间的这些差异。哥特人的迁徙、维京人的影响、伏尔加河地区的德国定居点和/或强迫人口重新安置以及与第二次世界大战相关的其他事件是可能导致这些发现的历史事件。
