Lehocký Ivan, Baldovic Marian, Kádasi Ludevít, Metspalu Ene
Department of Forensic Biology and DNA Analyse, Institute of Forensic Science of Police Corps, Bratislava, Slovak Republic.
Forensic Sci Int Genet. 2008 Sep;2(4):e53-9. doi: 10.1016/j.fsigen.2007.12.008. Epub 2008 Feb 14.
In order to identify polymorphic positions and to determine their frequencies and the frequency of haplotypes in the human mitochondrial control region, two hypervariable regions (HV1 and HV2) of the mitochondrial DNA (mtDNA) of 374 unrelated individuals from Slovakia were amplified and sequenced. Sequence comparison led to the identification of 284 mitochondrial lineages as defined by 163 variable sites. Genetic diversity (GD) was estimated at 0.997 and the probability of two randomly selected individuals from population having identical mtDNA types (random match probability, RMP) for the both regions is 0.60%.
为了识别多态性位点，确定其频率以及人类线粒体控制区单倍型的频率，对来自斯洛伐克的374名无亲缘关系个体的线粒体DNA（mtDNA）的两个高变区（HV1和HV2）进行了扩增和测序。序列比较导致识别出由163个可变位点定义的284个线粒体谱系。遗传多样性（GD）估计为0.997，从该人群中随机选择的两个个体具有相同mtDNA类型的概率（随机匹配概率，RMP）对于这两个区域均为0.60%。
Zotero 插件