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中国土家族Y染色体短串联重复序列单倍型的群体遗传学研究

Population genetics for Y-chromosomal STRs haplotypes of Chinese Tujia ethnic group.

作者信息

Shi Meisen, Bai Rufeng, Wan Lihua, Yu Xiaojun, Chang Lin

机构信息

Institute of Evidence Law and Forensic Science, China University of Political Science and Law, Beijing, PR China.

出版信息

Forensic Sci Int Genet. 2008 Sep;2(4):e65-8. doi: 10.1016/j.fsigen.2007.12.010. Epub 2008 Feb 14.

Abstract

Allele and haplotype frequencies of 11 Y-chromosomal short tandem repeats (STRs) included in the PowerPlex Y Systems (Promega) were determined in a sample of 215 unrelated healthy male individuals of Chinese Tujia ethnic group living in Chongqing (Southwest of China). The gene diversity values of the Y-STRs loci ranged from 0.3757(DYS391) to 0.9170 (DYS385a/b). A total of 195 haplotypes were identified in the Y-STR loci, among which 180 were unique, 11 were found in two individuals, 3 were shared in three individuals and 1 was shared in four individuals. The observed haplotype diversity value and discrimination capacity were 0.9942 and 0.9070, respectively.

摘要

在居住于中国西南部重庆的215名土家族健康男性无关个体样本中,测定了PowerPlex Y系统(Promega公司)中包含的11个Y染色体短串联重复序列(STR)的等位基因频率和单倍型频率。Y-STR基因座的基因多样性值范围为0.3757(DYS391)至0.9170(DYS385a/b)。在Y-STR基因座中共鉴定出195种单倍型,其中180种是独特的,11种在两个个体中出现,3种在三个个体中共享,1种在四个个体中共享。观察到的单倍型多样性值和鉴别能力分别为0.9942和0.9070。

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