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斯洛伐克东部高加索人和罗姆人(吉普赛人)群体中15个常染色体STR基因座的遗传变异分析。

Genetic variation analysis of 15 autosomal STR loci in Eastern Slovak Caucasian and Romany (Gypsy) population.

作者信息

Soták M, Petrejcíková E, Bernasovská J, Bernasovský I, Sovicová A, Boronová I, Svicková P, Bôziková A, Gabriková D

机构信息

Department of Biology, Faculty of Humanities and Natural Sciences, Presov University, 17 Novembra c. 1, 08116 Presov, Slovakia.

出版信息

Forensic Sci Int Genet. 2008 Dec;3(1):e21-5. doi: 10.1016/j.fsigen.2008.04.002. Epub 2008 May 20.

Abstract

The genotype polymorphism studies were carried out on two different populations: Eastern Slovak Caucasian (138) and Romany (Gypsy) (138), both from the town of Presov, at 15 highly polymorphic short tandem repeats (STRs) loci. The selected kit PowerPlex 16 system (Promega) included amelogenin, two penta-nucleotide repeats and 13 tetra-nucleotide repeats. The comparison of the allele frequencies between Eastern Slovak Caucasians and Romanies has shown significant differences in the majority of the focused loci. The P-values of exact test for Hardy-Weinberg equilibrium probabilities, observed and expected heterozygosity, matching probability, power of discrimination and exclusion, polymorphic information content, typical paternity index, genetic diversity and the other population-genetic indices were calculated.

摘要

在来自普雷绍夫镇的两个不同人群中开展了基因型多态性研究

138名东斯洛伐克高加索人以及138名罗姆人(吉卜赛人),研究针对15个高度多态性短串联重复序列(STR)位点进行。选用的PowerPlex 16系统试剂盒(普洛麦格公司)包含牙釉蛋白、两个五核苷酸重复序列以及13个四核苷酸重复序列。东斯洛伐克高加索人和罗姆人之间等位基因频率的比较显示,在大多数重点研究位点存在显著差异。计算了哈迪-温伯格平衡概率精确检验的P值、观察到的和预期的杂合性、匹配概率、鉴别力和排除力、多态信息含量、典型父权指数、遗传多样性以及其他群体遗传学指标。

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