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双源CT冠状动脉CT血管造影的图像质量与伪影:初步临床经验

Image quality and artifacts in coronary CT angiography with dual-source CT: initial clinical experience.

作者信息

Dey Damini, Lee Cynthia J, Ohba Muneo, Gutstein Ariel, Slomka Piotr J, Cheng Victor, Suzuki Yasuyuki, Suzuki Shoji, Wolak Arik, Le Meunier Ludovic, Thomson Louise E J, Cohen Ishac, Friedman John D, Germano Guido, Berman Daniel S

机构信息

Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building, A1258, Los Angeles, CA 90048, USA; David-Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

出版信息

J Cardiovasc Comput Tomogr. 2008 Mar-Apr;2(2):105-14. doi: 10.1016/j.jcct.2007.12.017. Epub 2008 Jan 15.

Abstract

INTRODUCTION

We aimed to characterize artifacts observed in a routine clinical coronary CT angiography (CCTA) performed by a dual-source CT (DSCT) scanner (Definition; Siemens Medical Solutions).

METHODS

Studies of 167 consecutive patients referred for CCTA, performed after beta-blockade (if not contraindicated), were prospectively analyzed for artifacts with a predefined visual approach. American Heart Association coronary segments (n = 2589) were assessed in 40%-80% R-R interval phases by 2 experts for stenosis, plaque presence or composition, and presence or type of artifacts. Each segment was considered evaluable when image quality was diagnostic in at least one cardiac phase. Artifacts included motion (cardiac, respiratory, patient), phase misregistration because of varying heart beats, calcified plaque blooming or beam hardening, metal beam hardening, large patient size, and contrast timing error.

RESULTS

Maximum HR (HR) during CCTA ranged from 45 to 120 beats/min (66.4 +/- 14.8 beats/min). Artifacts of some type were observed in 69 (41.3%) of 167 studies. Calcified plaque was the most common source of artifacts (14.4%), followed by misregistration (13.8%). Only 25 (1%) of 2589 coronary segments, in 6 (4%) of 167 patients were unevaluable, primarily because of calcified plaque blooming (coronary calcium score [CCS], 1112 +/- 1255]. Artifacts were associated with CCS (P = 0.002), change in HR (P = 0.01), age (P = 0.03), and body mass index (P = 0.048). The optimal phase for evaluation of all coronary arteries was 70% (mid-diastole), with a shift toward the systolic phases for HR > 70 beats/min.

CONCLUSION

CCTA artifacts with DSCT were related primarily to calcified plaque and cardiac phase misregistration. When correctly recognized, the artifacts did not have a serious effect on the final interpretation.

摘要

引言

我们旨在描述在使用双源CT(DSCT)扫描仪(Definition;西门子医疗解决方案公司)进行的常规临床冠状动脉CT血管造影(CCTA)中观察到的伪影。

方法

对167例因CCTA前来就诊的连续患者进行研究,这些研究在β受体阻滞剂治疗后(若未 contraindicated)进行,采用预定义的视觉方法对伪影进行前瞻性分析。由2名专家在40% - 80%的R - R间期阶段对美国心脏协会冠状动脉节段(n = 2589)进行狭窄、斑块存在或成分以及伪影的存在或类型评估。当图像质量在至少一个心动周期阶段具有诊断价值时,每个节段被视为可评估。伪影包括运动(心脏、呼吸、患者)、由于心跳变化导致的相位配准错误、钙化斑块光晕或线束硬化、金属线束硬化、患者体型较大以及对比剂注射时间误差。

结果

CCTA期间的最高心率(HR)范围为45至120次/分钟(66.4±14.8次/分钟)。在167项研究中的69项(41.3%)观察到某种类型的伪影。钙化斑块是最常见的伪影来源(14.4%),其次是配准错误(13.8%)。在2589个冠状动脉节段中,只有25个(1%),在167例患者中的6例(4%)不可评估,主要是由于钙化斑块光晕(冠状动脉钙化评分[CCS],1112±1255)。伪影与CCS(P = 0.002)、HR变化(P = 0.01)、年龄(P = 0.03)和体重指数(P = 0.048)相关。评估所有冠状动脉的最佳阶段是70%(舒张中期),对于HR > 70次/分钟,向收缩期阶段偏移。

结论

DSCT的CCTA伪影主要与钙化斑块和心脏相位配准错误有关。当正确识别时,伪影对最终解读没有严重影响。

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