School of Resource and Environmental Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Exp Parasitol. 2010 Jan;124(1):128-37. doi: 10.1016/j.exppara.2008.11.005. Epub 2008 Nov 27.
Cryptosporidium species are common parasites of wild placental mammals. Recent parasitological studies combined with molecular genotyping techniques have been providing valuable new insight into the host specificity and potential transmission of various Cryptosporidium species/genotypes among animals and between these animals and humans. Although Cryptosporidium in wild animals may possess a potential public health problem due to oocyst contamination in the environment, studies at various regions of the world have indicated a strong host-adaptation by these parasites and a limited potential of cross-species transmission of cryptosporidiosis among placental mammals, suggesting that these animals are probably not a major reservoir for human infection. However, Cryptosporidium species/genotypes in placental animals have been reported occasionally in humans. Therefore, public health significance of some Cryptosporidium species in wild placental mammals, such as the cervine genotype, should not be overlooked and should be further studied.
隐孢子虫是常见的野生有胎盘哺乳动物寄生虫。最近的寄生虫学研究结合分子基因分型技术，为各种隐孢子虫种/基因型在动物之间以及这些动物与人类之间的宿主特异性和潜在传播提供了有价值的新见解。尽管由于环境中的卵囊污染，野生动物中的隐孢子虫可能存在潜在的公共卫生问题，但在世界不同地区的研究表明，这些寄生虫具有很强的宿主适应性，在胎盘哺乳动物中发生隐孢子虫病的跨物种传播的潜力有限，这表明这些动物可能不是人类感染的主要宿主。然而，有胎盘动物中的隐孢子虫种/基因型偶尔也会在人类中报告。因此，一些野生有胎盘哺乳动物中的隐孢子虫（如鹿基因型）的公共卫生意义不应被忽视，应进一步研究。
