Frost Steven A, Alexandrou Evan, Bogdanovski Tony, Salamonson Yenna, Parr Michael J, Hillman Ken M
Liverpool Hospital, Sydney, Australia.
Resuscitation. 2009 Feb;80(2):224-30. doi: 10.1016/j.resuscitation.2008.10.030. Epub 2008 Dec 11.
Unplanned admission to an intensive care unit (ICU) is associated with high mortality, having the highest incidence among patients who are emergency admissions to the hospital. This study was designed to identify factors associated with unplanned ICU admission in emergency admissions to hospital and develop an absolute risk tool to individualise the risk of an event during a hospital stay.
Emergency department (ED) and in-patient hospital data from a large teaching hospital of consecutive admissions from 1 January 1997 to 31 December 2007 aged over 14 years was included in this study. Patient data extracted from 126826 emergency presentations admitted as in-patients consisted of demographic and clinical variables.
During an 11-year period 1582 incident unplanned ICU admissions occurred. Predictors of unplanned ICU admission included older age, being male, having a higher acuity triage category and a history of co-morbid conditions. Emergency department diagnostic groups associated with higher incidence of unplanned ICU admission included: sepsis, acute renal failure, lymphatic-hematopoietic tissue neoplasms, pneumonia, chronic-airways disease and bowel obstruction. The final model used to develop the nomogram had an ROC curve AUC of 0.7.
This study identified factors associated with unplanned ICU admission and developed a nomogram to individualise risk prior to a patient being transferred from the ED. This nomogram provides clinicians the opportunity prior to transfer from the ED, to either (1) review the appropriateness of the ward level of planned transfer or (2) flag patients for follow-up on the general ward to assess for deterioration.
重症监护病房(ICU)的非计划收治与高死亡率相关,在急诊入院患者中发生率最高。本研究旨在确定急诊入院患者中与ICU非计划收治相关的因素,并开发一种绝对风险工具,以个体化住院期间发生事件的风险。
本研究纳入了一家大型教学医院1997年1月1日至2007年12月31日连续收治的14岁以上患者的急诊科(ED)和住院数据。从126826例住院的急诊病例中提取的患者数据包括人口统计学和临床变量。
在11年期间,共发生1582例非计划ICU收治事件。非计划ICU收治的预测因素包括年龄较大、男性、分诊 acuity 类别较高以及有合并症病史。与非计划ICU收治发生率较高相关的急诊科诊断组包括:脓毒症、急性肾衰竭、淋巴造血组织肿瘤、肺炎、慢性气道疾病和肠梗阻。用于开发列线图的最终模型的ROC曲线AUC为0.7。
本研究确定了与ICU非计划收治相关的因素,并开发了一种列线图,以便在患者从急诊科转出之前个体化风险。该列线图为临床医生提供了在从急诊科转出之前的机会,要么(1)审查计划转入病房级别的适宜性,要么(2)标记普通病房需要随访的患者,以评估病情恶化情况。