Tam Victor, Frost Steven A, Hillman Ken M, Salamonson Yenna
Intensive Care Medicine, Liverpool Hospital, NSW, Australia.
Resuscitation. 2008 Nov;79(2):241-8. doi: 10.1016/j.resuscitation.2008.06.023. Epub 2008 Aug 8.
Although unplanned admissions to the intensive care unit (ICU) are associated with poorer prognoses, there is no published prognostic tool available for predicting this risk in an individual patient. We developed a nomogram for calculating the individualised absolute risk of unplanned ICU admission during a hospital stay.
Hospital administrative data from a large district hospital of consecutive admissions from 1 January 2000 to 31 December 2006 of aged over 14 years was used. Patient data was extracted from 94,482 hospital admissions consisted of demographic and clinical variables, including diagnostic categories, types of admission and time and day of admission. Multivariate logistic regression coefficients were used to develop a predictive nomogram of individual risk to patients admitted to the study hospital of unplanned ICU admission.
A total of 672 incident unplanned ICU admissions were identified over this period. Independent predictors of unplanned ICU admissions included being male, older age, emergency department (ED) admissions, after-hour admissions, weekend admissions and six principal diagnosis groups: fractured femur, acute pancreatitis, liver disease, chronic airway disease, pneumonia and heart failure. The area under the receiver operating characteristic curve was 0.81.
The use of a nomogram to accurately identify at-risk patients using information that is readily available to clinicians has the potential to be a useful tool in reducing unplanned ICU admissions, which in turn may contribute to the reduction of adverse events of patients in the general wards.
尽管重症监护病房(ICU)的非计划入院与较差的预后相关,但尚无已发表的预后工具可用于预测个体患者的这种风险。我们开发了一种列线图,用于计算住院期间非计划入住ICU的个体化绝对风险。
使用来自一家大型地区医院2000年1月1日至2006年12月31日连续收治的14岁以上患者的医院管理数据。从94482例住院患者中提取患者数据,包括人口统计学和临床变量,如诊断类别、入院类型以及入院时间和日期。多因素逻辑回归系数用于为研究医院收治的非计划入住ICU患者开发个体风险预测列线图。
在此期间共确定了672例非计划入住ICU的病例。非计划入住ICU的独立预测因素包括男性、年龄较大、急诊科入院、非工作时间入院、周末入院以及六个主要诊断组:股骨骨折、急性胰腺炎、肝病、慢性气道疾病、肺炎和心力衰竭。受试者工作特征曲线下面积为0.81。
使用列线图,利用临床医生易于获取的信息准确识别高危患者,有可能成为减少非计划入住ICU的有用工具,这反过来可能有助于减少普通病房患者的不良事件。