Mulhall John P
Sexual and Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
J Urol. 2009 Feb;181(2):462-71. doi: 10.1016/j.juro.2008.10.047. Epub 2008 Dec 13.
The contemporary literature pertaining to erectile dysfunction after radical prostatectomy was evaluated. The limitations of this literature are discussed and recommendations are made for the reporting of erectile function outcomes after radical prostatectomy.
A MEDLINE literature search was conducted in February 2008 to review English language articles published on this subject from 2000 onward. The key elements in defining and reporting erectile function outcomes after radical prostatectomy that were explored included 1) study population factors, 2) population demographics, 3) means of data acquisition, 4) variability in questionnaire use, 5) temporal considerations, 6) baseline erectile function status, 7) defining adequate erectile function, and the concepts of 8) quality and 9) consistency of erection.
The incidence of reported erectile dysfunction after radical prostatectomy is extremely discrepant. The rates of erectile dysfunction appear to be higher in multicenter, multisurgeon series compared to single center, single surgeon series. A total of 24 articles were culled from the literature, which are believed to be representative of the literature in this area. There was great variation in the nature of the populations studied, how data were acquired and reported, and how baseline and postoperative adequate erectile function was defined.
This review studies the strengths and weaknesses of the literature on erectile dysfunction after radical prostatectomy, and makes some general recommendations for investigating and reporting erectile function outcomes after radical prostatectomy.
对当代有关根治性前列腺切除术后勃起功能障碍的文献进行评估。讨论该文献的局限性，并对根治性前列腺切除术后勃起功能结果的报告提出建议。
2008年2月进行了MEDLINE文献检索，以回顾2000年以来发表的关于该主题的英文文章。探讨的根治性前列腺切除术后定义和报告勃起功能结果的关键要素包括：1）研究人群因素，2）人群人口统计学，3）数据获取方式，4）问卷使用的差异，5）时间因素，6）基线勃起功能状态，7）定义充分勃起功能，以及8）勃起质量和9）勃起一致性的概念。
根治性前列腺切除术后报告的勃起功能障碍发生率差异极大。与单中心、单术者系列相比，多中心、多术者系列中勃起功能障碍的发生率似乎更高。从文献中筛选出24篇文章，认为它们代表了该领域的文献。所研究人群的性质、数据获取和报告方式以及基线和术后充分勃起功能的定义存在很大差异。
本综述研究了根治性前列腺切除术后勃起功能障碍文献的优缺点，并对根治性前列腺切除术后勃起功能结果的调查和报告提出了一些一般性建议。
